Overview

  • Product name

  • Description

    Rabbit polyclonal to KIF1B
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human KIF1B aa 1547-1816.
    Database link: O60333

  • Positive control

    • IHC-P: Human skeletal muscle and small intestine tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab234869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Relevance

    KIF1B, or kinesin-like protein (Klp) functions as a motor for mitochondrial transport, and has a microtubule plus end-directed motility. The KIF1B beta isoform is abundant in brain, while the alpha isoform is abundant in skeletal muscle. Mutations in the KIF1B gene are the cause of Charcot-Marie-Tooth disease type 2A1, which is a primary peripheral axon neuropathy. The KIF1B beta isoform is down-regulated in sporadic amyotrophic lateral sclerosis (ALS).
  • Cellular localization

    Cytoplasmic and Mitochondrial
  • Database links

  • Alternative names

    • Charcot Marie Tooth neuropathy 2A antibody
    • CMT 2 antibody
    • CMT 2A antibody
    • CMT 2A1 antibody
    • CMT2 A antibody
    • CMT2 A1 antibody
    • CMT2 antibody
    • CMT2A 1 antibody
    • CMT2A antibody
    • CMT2A1 antibody
    • D4Mil1e antibody
    • HMSN II antibody
    • HMSNII antibody
    • HMSNII, hereditary motor sensory neuropathy II antibody
    • KIF 1B antibody
    • KIF1 B antibody
    • KIF1B p130 antibody
    • KIF1B p204 antibody
    • KIF1Bp130 antibody
    • KIF1Bp204 antibody
    • kinesin family member 1B antibody
    • Kinesin like protein KIF1B antibody
    • Klp antibody
    see all

Images

  • Paraffin-embedded human skeletal muscle tissue stained for KIF1B with ab234869 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human small intestine tissue stained for KIF1B with ab234869  at 1/100 dilution in immunohistochemical analysis.

References

ab234869 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab234869.
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