Anti-Kif2a antibody (ab3475)
Key features and details
- Rabbit polyclonal to Kif2a
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Kif2a antibody
See all Kif2a primary antibodies -
Description
Rabbit polyclonal to Kif2a -
Host species
Rabbit -
Specificity
Detects Kinesin 2 (Kif2a) from mouse tissues. -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rat, Chicken, Cow, Human, Xenopus laevis -
Immunogen
Synthetic peptide corresponding to Mouse Kif2a aa 1-11.
Sequence:MVTSLNEDNES
(Peptide available asab4992) -
Positive control
- Mouse brain homogenate.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Target
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Function
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. -
Sequence similarities
Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily.
Contains 1 kinesin-motor domain. -
Cellular localization
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton > spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1. - Information by UniProt
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Database links
- Entrez Gene: 3796 Human
- Entrez Gene: 16563 Mouse
- Entrez Gene: 84391 Rat
- Entrez Gene: 379622 Xenopus laevis
- Omim: 602591 Human
- SwissProt: O00139 Human
- SwissProt: P28740 Mouse
- SwissProt: Q9WV63 Rat
see all -
Alternative names
- CDCBM3 antibody
- HK2 antibody
- KIF2 antibody
see all
Datasheets and documents
References (0)
ab3475 has not yet been referenced specifically in any publications.