Anti-KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4 antibody (ab197927)

Overview

  • Product name

    Anti-KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4 antibody
  • Description

    Rabbit polyclonal to KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Fusion protein corresponding to Human KIR2DL1 + KIR2DL3 + KIR2DL4 + KIR2DS4 (internal sequence). (BC032422/ ADQ31987/ NP_002246/ NP_036446). The identity of protein fusion partner is GST.

  • Positive control

    • Human colon cancer and thyroid cancer tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab197927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/30 - 1/100.

Target

  • Relevance

    KIRs are human natural killer (NK) cell receptors for MHC class I molecules. Most inhibit the activity of NK cells thus preventing cell lysis. Two main families of receptors for HLA class I have been discovered on human NK cells: Killer cell Immunoglobulin-like receptors (KIR) and CD94/NKG2 heterodimers. The KIR receptors are an extremely diverse family of receptors. In addition to receptors for HLA, NK cells also express pattern recognition receptors e.g. TLRs and Nod proteins.
  • Cellular localization

    Cell Membrane
  • Database links

  • Alternative names

    • CD158D antibody
    • CD158I antibody
    • G9P antibody
    • Killer cell Ig like receptors antibody
    • Killer cell immunoglobulin like receptor 2DL3 antibody
    • KKA3 antibody
    • Natural killer cell inhibitory receptor antibody
    • NKAT antibody
    • NKAT1 antibody
    • NKAT2 antibody
    • NKAT8 antibody
    • p58 NK receptor antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling KIR2DL3 with ab197927 at 1/30 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling KIR2DL3 with ab197927 at 1/30 dilution.

References

ab197927 has not yet been referenced specifically in any publications.

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