Recombinant
RabMAb

Recombinant Anti-KIR2DL3 antibody [EPR22195] (ab224698)

Overview

  • Product name

    Anti-KIR2DL3 antibody [EPR22195]
    See all KIR2DL3 primary antibodies
  • Description

    Rabbit monoclonal [EPR22195] to KIR2DL3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human KIR2DL3 aa 1-250. The exact sequence is proprietary.
    Database link: P43628

  • Positive control

    • Flow Cyt: Primary human peripheral blood mononuclear cells.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: PBS, 40% Glycerol, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    EPR22195
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab224698 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/600.

Target

  • Function

    Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD158 antigen like family member B2 antibody
    • CD158 antigen-like family member B2 antibody
    • CD158b antibody
    • CD158b2 antibody
    • GL183 antibody
    • KI2L3_HUMAN antibody
    • Killer cell immunoglobulin like receptor two domains long cytoplasmic tail 3 antibody
    • Killer cell immunoglobulin-like receptor 2DL3 antibody
    • Killer inhibitory receptor cl 2-3 antibody
    • Killer inhibitory receptor CL2 3 antibody
    • KIR 023GB antibody
    • KIR-023GB antibody
    • KIR-K7b antibody
    • KIR-K7c antibody
    • KIR023GB antibody
    • KIR2DL3 antibody
    • KIR2DS5 antibody
    • KIRCL23 antibody
    • MHC class I NK cell receptor antibody
    • Natural killer associated transcript 2 antibody
    • Natural killer cell inhibitory receptor KIR2DL3 antibody
    • Natural killer-associated transcript 2 antibody
    • NKAT antibody
    • NKAT-2 antibody
    • NKAT2 antibody
    • NKAT2a antibody
    • NKAT2b antibody
    • p58 antibody
    • p58 natural killer cell receptor clone CL 6 antibody
    • p58 natural killer cell receptor clone CL-6 antibody
    • p58 NK Receptor antibody
    • p58 NK receptor CL 6 antibody
    • p58 NK receptor CL-6 antibody
    • p58.2 MHC class I specific NK receptor antibody
    • p58.2 MHC class-I-specific NK receptor antibody
    see all

Images

  • Flow cytometric analysis of primary human peripheral blood mononuclear cells (PBMC) labeling KIR2DL3 with ab224698 at 1/600 dilution (right panel) compared with a Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730) (left panel). Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) preadsorbed (ab150081) at 1/2000 dilution was used as the secondary antibody.

    Human peripheral blood mononuclear cells were stained with PE-conjugated CD56 and rabbit IgG (Left) or KIR2DL3 (Right). Data shown were gated on viable cells.

References

ab224698 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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