For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Take a look at our BETA site and see what we’ve done so far.
Search and browse selected products
Purchase these through your usual distributor
Caspase activation is an essential step of the apoptotic cascade that leads to cell death.
The two main pathways through which apoptotic cell death is initiated are the intrinsic and extrinsic cell death pathways, characterized by caspase 9 and caspase 8 activation, respectively.
Assays that determine caspase activity through cleavage of biochemical substrates are a quick and convenient method to assess caspase activation in cells. However, caution is recommended when interpreting the data from these experiments due to the following factors:
The tables below show known cross-reactivities with other caspases.