Key features and details
- Rabbit polyclonal to KLC1
- Suitable for: ICC/IF, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-KLC1 antibody
See all KLC1 primary antibodies
DescriptionRabbit polyclonal to KLC1
Tested applicationsSuitable for: ICC/IF, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant full length protein corresponding to Human KLC1.
Database link: Q07866
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab187179 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use at an assay dependent concentration.|
|WB||1/500 - 1/2000. Predicted molecular weight: 65 kDa.|
FunctionKinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Tissue specificityFound in a variety of tissues. Mostly abundant in brain and spine.
Sequence similaritiesBelongs to the kinesin light chain family.
Contains 6 TPR repeats.
modificationsIsoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631.
Cellular localizationCytoplasm > cytoskeleton.
- Information by UniProt
- Kinesin 2 60/70kDa antibody
- Kinesin light chain 1 antibody
- Kinesin2 antibody
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab187179. Blue DAPI for nuclear staining.
All lanes : Anti-KLC1 antibody (ab187179) at 1/500 dilution
Lane 1 : SW480 cell extract
Lane 2 : 22RV1 cell extract
Lane 3 : BT474 cell extract
Lane 4 : MCF7 cell extract
Lane 5 : Mouse brain cell extract
Predicted band size: 65 kDa
ab187179 has been referenced in 3 publications.
- Dinamarca MC et al. Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing. Nat Commun 10:1331 (2019). PubMed: 30902970
- Holt I et al. Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle. Sci Rep 9:14202 (2019). PubMed: 31578382
- Jang WH et al. Interaction of FUN14 domain containing 1, a mitochondrial outer membrane protein, with kinesin light chain 1 via the tetratricopeptide repeat domain. Biomed Rep 6:46-50 (2017). PubMed: 28123706