Overview

  • Product name

  • Description

    Rabbit polyclonal to KLC1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide within Human KLC1 aa 389-415 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: Q07866

  • Positive control

    • WB: HeLa cell lysate. IHC-P: Human cerebellum tissue. Flow Cyt: WiDr cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab230859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 65 kDa.
IHC-P 1/50 - 1/100.
Flow Cyt 1/10 - 1/50.

Target

  • Function

    Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
  • Tissue specificity

    Found in a variety of tissues. Mostly abundant in brain and spine.
  • Sequence similarities

    Belongs to the kinesin light chain family.
    Contains 6 TPR repeats.
  • Post-translational
    modifications

    Isoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631.
  • Cellular localization

    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • Kinesin 2 60/70kDa antibody
    • Kinesin light chain 1 antibody
    • Kinesin2 antibody
    • KLC 1 antibody
    • KLC antibody
    • Klc1 antibody
    • KLC1_HUMAN antibody
    • KNS 2 antibody
    • KNS 2A antibody
    • KNS2 antibody
    • KNS2A antibody
    • Medulloblastoma antigen MU MB 2.50 antibody
    • MGC15245 antibody
    see all

Images

  • Anti-KLC1 antibody (ab230859) at 1/1000 dilution + HeLa (human epithelial cell line from cervix adenocarcinoma) cell lysate. at 35 µg

    Predicted band size: 65 kDa

  • Formalin-fixed, paraffin-embedded human cerebellum tissue stained for KLC1 using ab230859 at 1/50 dilution in immunohistochemical analysis.

  • Flow cytometric analysis of WiDr cells labeling KLC1 with ab230859 at 1/10 dilution (green) compared with a negative control (blue).

    FITC-conjugated goat-anti-rabbit secondary antibodies were used.

References

ab230859 has not yet been referenced specifically in any publications.

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