Product nameKLC1 peptide
Our Abpromise guarantee covers the use of ab4992 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human KIF 1, catalog ab3475. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Reconstitution>95% pure, lyophilized synthetic peptide. Reconstitute with 0.1 ml of distilled water.
- Kinesin 2 60/70kDa
- Kinesin light chain 1
FunctionKinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Tissue specificityFound in a variety of tissues. Mostly abundant in brain and spine.
Sequence similaritiesBelongs to the kinesin light chain family.
Contains 6 TPR repeats.
modificationsIsoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631.
Cellular localizationCytoplasm > cytoskeleton.
- Information by UniProt
ab4992 has not yet been referenced specifically in any publications.