ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
Belongs to the Sp1 C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers.
Flow cytometric analysis of Hela cells labeling KLF17 with ab174956 at 1/10 dilution (right histogram) compared to negative control cells (left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis.
Western blot - Anti-KLF17 antibody - C-terminal (ab174956)
Anti-KLF17 antibody - C-terminal (ab174956) at 1/100 dilution + HeLa cell lysate at 35 µg