Product nameAnti-KLF2 antibody
See all KLF2 primary antibodies
DescriptionGoat polyclonal to KLF2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow, Dog, Pig, Xenopus laevis
- Human heart lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of ab17008 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 1.5 - 3 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 41 kDa) from human heart lysates.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionBinds to the CACCC box in the beta-globin gene promoter and activates transcription.
Sequence similaritiesBelongs to the krueppel C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.
modificationsUbiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.
- Information by UniProt
- KLF 2 antibody
- Klf2 antibody
- KLF2_HUMAN antibody
ab17008 at 1.5
µg/ml detecting KLF2 from human heart lysate by Western blot. 35 µg of total protein was loaded per lane. Primary antibody was incubated for 1 hour. The blot was detected using chemiluminescence.
This product has been referenced in:
- Zou K et al. Krüppel-like factor 2 promotes cell proliferation in hepatocellular carcinoma through up-regulation of c-myc. Cancer Biol Ther 17:20-6 (2016). Read more (PubMed: 26853883) »
- Tuomisto TT et al. Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2. Cardiovasc Res 78:175-84 (2008). Read more (PubMed: 18192240) »