Anti-KLF8 antibody - N-terminal (ab229674)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-KLF8 antibody - N-terminal
See all KLF8 primary antibodies -
Description
Rabbit polyclonal to KLF8 - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC - Wholemountmore details -
Species reactivity
Reacts with: Zebrafish -
Immunogen
Recombinant fragment within Zebrafish KLF8 (N terminal). The exact sequence is proprietary.
Database link: A0S0R1 -
Positive control
- IHC - Wholemount: 1 day-post-fertilization zebrafish embryo.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin
Constituents: PBS, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab229674 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC - Wholemount | 1/50 - 1/500. |
Target
-
Function
Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). -
Tissue specificity
Ubiquitous. -
Sequence similarities
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers. -
Post-translational
modificationsSumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G(1) phase. Has no effect on subcellular location. -
Cellular localization
Nucleus. - Information by UniProt
-
Alternative names
- Basic krueppel-like factor 3 antibody
- BKLF3 antibody
- DXS741 antibody
see all
Images
-
IHC - Wholemount - Anti-KLF8 antibody - N-terminal (ab229674)Whole mount 1 day-post-fertilization zebrafish embryo tissue stained for KLF8 using ab229674 at 1/50 dilution in immunohistochemical analysis.
References
ab229674 has not yet been referenced specifically in any publications.
