Overview

  • Product name

  • Description

    Rabbit polyclonal to KLHL13
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human KLHL13 aa 1-260.
    Database link: Q9P2N7

  • Positive control

    • IHC-P: Human ovarian cancer and prostate cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Contains 1 BACK (BTB/Kelch associated) domain.
    Contains 1 BTB (POZ) domain.
    Contains 6 Kelch repeats.
  • Information by UniProt
  • Database links

  • Alternative names

    • BKLHD2 antibody
    • BTB and kelch domain containing 2 antibody
    • BTB and kelch domain containing 2 KIAA1309 antibody
    • BTB and kelch domain containing protein 2 antibody
    • BTB and kelch domain-containing protein 2 antibody
    • FLJ10262 antibody
    • Kelch like 13 (Drosophila) antibody
    • Kelch like protein 13 antibody
    • Kelch-like protein 13 antibody
    • KIAA1309 antibody
    • KLH13_HUMAN antibody
    • KLHL13 antibody
    • MGC74791 antibody
    see all

Images

  • Paraffin-embedded human ovarian cancer tissue stained for KLHL13 using ab230264 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human prostate cancer tissue stained for KLHL13 using ab230264 at 1/100 dilution in immunohistochemical analysis.

References

ab230264 has not yet been referenced specifically in any publications.

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