Overview

  • Product name

    Anti-KLRG1 antibody [2F1] (violetFluor™ 450)
    See all KLRG1 primary antibodies
  • Description

    Syrian hamster monoclonal [2F1] to KLRG1 (violetFluor™ 450)
  • Host species

    Syrian hamster
  • Conjugation

    violetFluor™ 450
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Flow Cyt: Mouse C57Bl/6 splenocytes.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Store In the Dark.
  • Storage buffer

    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin
  • Concentration information loading...
  • Purity

    Affinity purified
  • Purification notes

    Purified from TCS.
  • Clonality

    Monoclonal
  • Clone number

    2F1
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab242067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

0.125 μg: The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.

Target

  • Function

    Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
  • Tissue specificity

    Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
  • Sequence similarities

    Contains 1 C-type lectin domain.
  • Domain

    Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. Upon phosphorylation of ITIM motif KLRG1 associates with the two phosphatases PTPN11 and INPP5D.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 2F1 Ag antibody
    • 2F1 antibody
    • C type lectin domain family 15 member A antibody
    • C-type lectin domain family 15 member A antibody
    • CLEC15A antibody
    • ITIM containing receptor MAFA L antibody
    • ITIM-containing receptor MAFA-L antibody
    • Killer cell lectin like receptor G1 antibody
    • Killer cell lectin like receptor subfamily G member 1 antibody
    • Killer cell lectin-like receptor subfamily G member 1 antibody
    • KLRG 1 antibody
    • KLRG1 antibody
    • KLRG1 protein antibody
    • KLRG1_HUMAN antibody
    • MAFA 2F1 antibody
    • MAFA antibody
    • MAFA L antibody
    • MAFA like antibody
    • MAFA like receptor antibody
    • MAFA-like receptor antibody
    • MAFAL antibody
    • Mast cell function associated antigen (ITIM containing) antibody
    • Mast cell function associated antigen antibody
    • Mast cell function-associated antigen 2F1 antibody
    • Mast cell function-associated antigen antibody
    • Mast cell function-associated antigen, rat, homolog of antibody
    • MGC13600 antibody
    see all

Images

  • Flow cytometric analysis of mouse C57Bl/6 splenocyte cells staining KLRG1 using PE Anti-Mouse NK1.1 and 0.125 µg ab242067 (right panel) or 0.125 µg violetFluor 450 Syrian Hamster IgG isotype control (left panel).

References

ab242067 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab242067.
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