Product nameAnti-KMT3A / HYPB / HIF-1 antibody - C-terminal
See all KMT3A / HYPB / HIF-1 primary antibodies
DescriptionRabbit polyclonal to KMT3A / HYPB / HIF-1 - C-terminal
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Fusion protein corresponding to Human KMT3A/ HYPB/ HIF-1 (C terminal).
Database link: Q9BYW2
- Human tonsil cancer and Human cervical cancer tissues.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.3
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab197840 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
FunctionHistone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. Probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. Binds DNA at promoters. May also act as a transcription activator that binds to promoters. Binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.
Tissue specificityUbiquitously expressed.
Sequence similaritiesBelongs to the histone-lysine methyltransferase family. SET2 subfamily.
Contains 1 AWS domain.
Contains 1 post-SET domain.
Contains 1 SET domain.
Contains 1 WW domain.
DomainThe low charge region mediates the transcriptional activation activity.
modificationsMay be automethylated.
Cellular localizationNucleus. Chromosome.
- Information by UniProt
- EC 22.214.171.124 antibody
- FLJ16420 antibody
- FLJ22472 antibody
ab197840 has not yet been referenced specifically in any publications.