Overview

  • Product name

    Anti-KMT4 / Dot1L antibody - C-terminal
    See all KMT4 / Dot1L primary antibodies
  • Description

    Rabbit polyclonal to KMT4 / Dot1L - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human KMT4/ Dot1L (C terminal). The exact sequence is proprietary. (Carrier-protein conjugated).
    Database link: Q8TEK3

  • Positive control

    • WB: NCI-H1299 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab228766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 185 kDa.

Target

  • Function

    Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
  • Sequence similarities

    Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
    Contains 1 DOT1 domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Disrupter of telomere silencing protein 1 antibody
    • DOT 1 antibody
    • DOT1 antibody
    • DOT1 like antibody
    • DOT1 like histone H3 methyltransferase (S. cerevisiae) antibody
    • DOT1 like histone H3 methyltransferase antibody
    • DOT1 like histone H3K79 methyltransferase antibody
    • DOT1 like protein antibody
    • DOT1, S. cerevisiae, homolog of antibody
    • DOT1-like protein antibody
    • DOT1L antibody
    • DOT1L_HUMAN antibody
    • EC 2.1.1.43 antibody
    • H3 K79 HMTase antibody
    • H3 lysine-79 specific antibody
    • H3-K79-HMTase antibody
    • Histone H3 K79 methyltransferase antibody
    • Histone H3 methyltransferase antibody
    • Histone H3 methyltransferase DOT1-like antibody
    • Histone H3-K79 methyltransferase antibody
    • Histone lysine N methyltransferase H3 lysine 79 specific antibody
    • Histone methyltransferase DOT1L antibody
    • Histone-lysine N-methyltransferase antibody
    • KIAA1814 antibody
    • KMT4 antibody
    • Lysine N methyltransferase 4 antibody
    • Lysine N-methyltransferase 4 antibody
    see all

Images

  • Anti-KMT4 / Dot1L antibody - C-terminal (ab228766) at 1/1000 dilution + NCI-H1299 (human lung carcinoma cell line) whole cell lysate

    Predicted band size: 185 kDa

References

ab228766 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228766.
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