Cell Invasion Assay Kit (Collagen I), 24-well, 8 µm

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This kit provides enough materials for 12 assays, i.e. to run 12 wells of assay, although it comes in a 24 well plate format.

Cell Invasion Assay (Collagen I), 24-well, 8 μm (ab235887) utilizes a Boyden chamber coated with collagen I, where the cells invade the matrix and then migrate through a semipermeable membrane in the Boyden chamber in response to stimulants or inhibitory compounds. The percent cell invasion can be analyzed directly in a plate reader. Our assay is easy to use, sensitive and adaptable to high-throughput systems.

This product is manufactured by BioVision, an Abcam company and was previously called K917 EZCellTM Cell Invasion Assay Kit (Collagen I), 12-well, 8 μm. K917-12 is the same size as the 12 test size of ab235887.

Cell invasion is the ability of cells to migrate from one area to another through an extracellular matrix. Cell invasion is exhibited by both normal cells as well as cancerous cells in response to specific external signals, including chemical & mechanical stimuli. During invasion, extracellular matrix is enzymatically degraded by cellular proteases before cells migrate to the new location. Cell invasion is required for normal processes such as wound repair, vasculature formation and the inflammatory response as well as the abnormal invasion of tissues by tumor cells during metastasis.

The Safety Datasheet for this product has been updated for certain countries. Please check the current version in the Support and downloads section.