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AB145305

5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker

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(1 출판물)

MW 347.3 Da, Purity >95%. Fluorescence marker. Selectively targets malignant glioma tissue in vivo when covalently linked to human serum albumin at a molar ratio of 1:1without bleaching nor penetrating into surrounding brain edema or necrotic tissue. Blood-brain barrier permeable.
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Chemical Structure - 5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker (AB145305)
  • Chemical Structure

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Chemical Structure - 5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker (AB145305)

2D chemical structure image of ab145305, 5-Aminofluorescein (Fluoresceinamine, isomer I), Fluorescence marker

주요 정보

CAS 번호

3326-34-9

Purity

>95%

제형

Solid

form

Molecular weight

347.3 Da

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>1</sub><sub>3</sub>NO<sub>5</sub>

PubChem

76845

Nature

Synthetic

생화학적 명칭

5-Aminofluorescein

생물학적 정보

Fluorescence marker. Selectively targets malignant glioma tissue in vivo when covalently linked to human serum albumin at a molar ratio of 1:1without bleaching nor penetrating into surrounding brain edema or necrotic tissue. Blood-brain barrier permeable.

Canonical SMILES

C1=CC2=C(C=C1N)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O

InChi

InChI=1S/C20H13NO5/c21-10-1-4-14-13(7-10)19(24)26-20(14)15-5-2-11(22)8-17(15)25-18-9-12(23)3-6-16(18)20/h1-9,22-23H,21H2

InChiKey

GZAJOEGTZDUSKS-UHFFFAOYSA-N

IUPAC Name

6-amino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one

Excitation/Emission

Ex: 490nm, Em: 520nm

특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
Ambient
적절한 장기 보관 조건
Ambient
보관 정보
Store under desiccating conditions|The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

제품 프로토콜

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

eLife 13: PubMed39641975

2024

Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration.

Applications

Unspecified application

Species

Unspecified reactive species

Debabrata Dey,Shir Marciano,Anna Poryval,Ondřej Groborz,Lucie Wohlrabova,Tomás Slanina,Gideon Schreiber
제품이 사용된 논문 모두 보기

Product promise

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