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AB146746

6-Thio-GTP (aqueous solution) (Thiogtp), Vac-1-Rac signaling inhibitor

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(1 Publication)

MW 539.24 g/mol, Purity >95%. Vac-1-Rac signaling inhibitor. Azathioprine (ab143064) metabolite. 6-mercaptopurine (ab142389) derivative. Inhibits TNF-α-induced downstream signaling via JNK. Reduces c-Jun, transcription factor-2 and NF-κB activation. Shows immunosuppressant effects.
1 Images
Chemical Structure - 6-Thio-GTP (aqueous solution) (Thiogtp), Vac-1-Rac signaling inhibitor (AB146746)
  • Chemical Structure

Lab

Chemical Structure - 6-Thio-GTP (aqueous solution) (Thiogtp), Vac-1-Rac signaling inhibitor (AB146746)

2D chemical structure image of ab146746, 6-Thio-GTP (aqueous solution) (Thiogtp), Vac-1-Rac signaling inhibitor

주요 정보

CAS 번호

17670-19-8

Purity

>95%

제형

Liquid

form

Molecular weight

539.24 g/mol

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>6</sub>N<sub>5</sub>O<sub>1</sub><sub>3</sub>P<sub>3</sub>S

Nature

Synthetic

생물학적 정보

Vac-1-Rac signaling inhibitor. Azathioprine (ab143064) metabolite. 6-mercaptopurine (ab142389) derivative. Inhibits TNF-α-induced downstream signaling via JNK. Reduces c-Jun, transcription factor-2 and NF-κB activation. Shows immunosuppressant effects.

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보완 제품

Biochemicals

AB141024

AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist

Chemical Structure - AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist (AB141024)

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Biochemicals

AB120170

Substance P, Sensory neuropeptide

Chemical Structure - Substance P, Sensory neuropeptide (AB120170)

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Biochemicals

AB141296

Indirubin-3'-monoxime, GSK3beta inhibitor. CDK inhibitor.

Chemical Structure - Indirubin-3'-monoxime, GSK3beta inhibitor. CDK inhibitor. (AB141296)

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Biochemicals

AB141257

5'-Deoxy-5'-methylthioadenosine (Methylthioadenosine), Adenosine A1 receptor agonist

Chemical Structure - 5'-Deoxy-5'-methylthioadenosine (Methylthioadenosine), Adenosine A1 receptor agonist (AB141257)

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특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Store under desiccating conditions
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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제품 프로토콜

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of molecular sciences 25: PubMed39519032

2024

Dennd2c Negatively Controls Multinucleation and Differentiation in Osteoclasts by Regulating Actin Polymerization and Protrusion Formation.

Applications

Unspecified application

Species

Unspecified reactive species

Yu Koyanagi,Eiko Sakai,Yu Yamaguchi,Fatima Farhana,Yohsuke Taira,Kuniaki Okamoto,Hiroshi Murata,Takayuki Tsukuba
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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