JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB120141

Apigenin, Anticancer agent

Be the first to review this product! 리뷰 제출

|

(1 출판물)

MW 270.24 Da, Purity >98%. Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.
2 이미지
Functional Studies - Apigenin, Anticancer agent (AB120141)
  • FuncS

PubMed

Functional Studies - Apigenin, Anticancer agent (AB120141)

(A-D). The release of cytokines as assessed using Human Cytokine Array C1000 membranes from MDA-MB-231 cells ± TNFα ± Apigenin. [A] Ctrls, [B] TNFα-treated (40ng/mL) [C] Apigenin (40μM) and [D] TNFα-treated (40ng/mL) + Apigenin (40μM) co-treated cells.

Bauer et al PLoS One. 2017 Apr 25;12(4):e0175558. doi: 10.1371/journal.pone.0175558. eCollection 2017. Fig 2. Reproduced under the Creative Commons license https://creativecommons.org/publicdomain/zero/1.0/

Chemical Structure - Apigenin, Anticancer agent (AB120141)
  • Chemical Structure

Lab

Chemical Structure - Apigenin, Anticancer agent (AB120141)

2D chemical structure image of ab120141, Apigenin, Anticancer agent

주요 정보

CAS 번호

520-36-5

Purity

>98%

제형

Solid

form

Molecular weight

270.24 Da

Molecular formula

C<sub>1</sub><sub>5</sub>H<sub>1</sub><sub>0</sub>O<sub>5</sub>

PubChem

5280443

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

생화학적 명칭

Apigenin

생물학적 정보

Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.

Canonical SMILES

C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O

InChi

InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H

InChiKey

KZNIFHPLKGYRTM-UHFFFAOYSA-N

IUPAC Name

5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Store under desiccating conditions|The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

|

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

|

Refer to SDS for further information.

제품 프로토콜

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

PloS one 12:e0175558 PubMed28441391

2017

Apigenin inhibits TNFα/IL-1α-induced CCL2 release through IKBK-epsilon signaling in MDA-MB-231 human breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

David Bauer,Natalie Redmon,Elizabeth Mazzio,Karam F Soliman
제품이 사용된 논문 모두 보기

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com