BML-278, SIRT activator

주요 정보

CAS 번호

120533-76-8

Purity

>98%

Molecular weight

391.5 Da

Molecular formula

C₂₄H₂₅NO₄

PubChem

10620479

Nature

Synthetic

Solubility

Soluble in DMSO to 10 mM

생화학적 명칭

Diethyl 1-benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate

생물학적 정보

Potent, cell-permeable SIRT activator. Shows selectivity for SIRT1. Induces cell cycle arrest at G1/S phase.

Canonical SMILES

CCOC(=O)C1=CN(C=C(C1C2=CC=CC=C2)C(=O)OCC)CC3=CC=CC=C3

InChi

InChI=1S/C24H25NO4/c1-3-28-23(26)20-16-25(15-18-11-7-5-8-12-18)17-21(24(27)29-4-2)22(20)19-13-9-6-10-14-19/h5-14,16-17,22H,3-4,15H2,1-2H3

IUPAC Name

diethyl 1-benzyl-4-phenyl-4H-pyridine-3,5-dicarboxylate