AB142036

Boc-D-FMK, caspase inhibitor

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(3 제품이 사용된 논문 )

MW 263.26 Da. Irreversible general caspase inhibitor. Blocks hepatocyte apoptosis in vivo. Active in vitro and in vivo. Cell-permeable.

1 이미지

Chemical Structure - Boc-D-FMK, caspase inhibitor (AB142036)

Chemical Structure

Lab

Chemical Structure - Boc-D-FMK, caspase inhibitor (AB142036)

2D chemical structure image of ab142036, Boc-D-FMK, caspase inhibitor

주요 정보

CAS 번호

634911-80-1

제형

Solid

form

Molecular weight

263.26 Da

Molecular formula

C11H18FNO5

PubChem

16760348

Nature

Synthetic

Solubility

Soluble in DMSO to 20 mM

생화학적 명칭

Boc-D-FMK

생물학적 정보

Irreversible general caspase inhibitor. Blocks hepatocyte apoptosis in vivo. Active in vitro and in vivo. Cell-permeable.

Canonical SMILES

CC(C)(C)OC(=O)NC(CC(=O)OC)C(=O)CF

InChi

InChI=1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)

InChiKey

MXOOUCRHWJYCAL-UHFFFAOYSA-N

IUPAC Name

methyl 5-fluoro-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxopentanoate

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특성 및 보관 정보

배송 시 보관 조건

Ambient - Can Ship with Ice

적절한 단기 보관 조건

-20°C

적절한 장기 보관 조건

-20°C

보관 정보

Store under desiccating conditions|The product can be stored for up to 12 months

취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Refer to SDS for further information.

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제품 프로토콜

Visit the General protocols
Visit the Troubleshooting

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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of biological methods 11:e99010040 PubMed39839094

2025

Reappraisal of the fundamental mechanisms of the sHA14-1 molecule as a Bcl-2/Bcl-XL ligand in the context of anticancer therapy: A cell biological study.

Applications

Unspecified application

Species

Unspecified reactive species

Aoula Moustapha,Pauline Andreu,François Gonzalvez,Delphine Fradin,Jean-Pierre Tissier,Phillippe Diolez,Patrice Xavier Petit

eNeuro 8: PubMed33372032

2021

NGF-Dependent and BDNF-Dependent DRG Sensory Neurons Deploy Distinct Degenerative Signaling Mechanisms.

Applications

Unspecified application

Species

Unspecified reactive species

Andrés de León,Julien Gibon,Philip A Barker

Cell death & disease 6:e1864 PubMed26313915

2015

CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells.

Applications

Unspecified application

Species

Unspecified reactive species

X Qiu,C Klausen,J-C Cheng,P C K Leung

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Boc-D-FMK, caspase inhibitor

Chemical Structure - Boc-D-FMK, caspase inhibitor (AB142036)

주요 정보

CAS 번호

제형

Molecular weight

Molecular formula

PubChem

Nature

Solubility

생화학적 명칭

생물학적 정보

Canonical SMILES

InChi

InChiKey

IUPAC Name

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

특성 및 보관 정보

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

보관 정보

취급 방법

제품 프로토콜

제품이 사용된 논문 (3)

Product promise