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AB144214

bpV(HOpic), PTP and PTEN inhibitor

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MW 347.24 g/mol, Purity >95%. Inhibits PTP (IC50 = 4-25 μM) and PTEN (IC50 = 14 nM). Insulin mimetic. Enhances PI3K/Akt signaling and possibly prevents myocardium from ischemia-reperfusion injury. Active in vitro.
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Chemical Structure - bpV(HOpic), PTP and PTEN inhibitor (AB144214)
  • Chemical Structure

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Chemical Structure - bpV(HOpic), PTP and PTEN inhibitor (AB144214)

2D chemical structure image of ab144214, bpV(HOpic), PTP and PTEN inhibitor

주요 정보

CAS 번호

722494-26-0

Purity

>95%

제형

Solid

form

Molecular weight

347.24 g/mol

Molecular formula

C<sub>6</sub>H<sub>4</sub>K<sub>2</sub>NO<sub>8</sub>V

Nature

Synthetic

Solubility

Soluble in DMSO

생물학적 정보

Inhibits PTP (IC50 = 4-25 μM) and PTEN (IC50 = 14 nM). Insulin mimetic. Enhances PI3K/Akt signaling and possibly prevents myocardium from ischemia-reperfusion injury. Active in vitro.

InChi

InChI=1S/C6H5NO3.2K.2O2.O.V/c8-4-1-2-5(6(9)10)7-3-4;;;2*1-2;;/h1-3,8H,(H,9,10);;;;;;/q;2*+1;2*-2;;+3/p-1

InChiKey

IZLHQXYPQCZJAG-UHFFFAOYSA-M

IUPAC Name

Dipotassium bisperoxo(5-hydroxypyridine-2-carboxyl)oxovanadate (V)

제품 세부 정보

This product is not stable in water; immediately upon dissolution decomposition starts to occur. Decomposition in dry DMSO has also been observed but at a slower rate.

특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

제품 프로토콜

Product promise

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