CD 437, RARgamma-selective agonist.

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MW 398.5 Da, Purity >99%. Potent, cell-permeable RARγ-selective agonist (EC₅₀ values are 140, 28 and 7 nM for RAR-α, β and γ respectively). Shows RARγ-dependent and -independent effects on differentiation and apoptosis. Shows antitumor effects in vivo..

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1,8-cineole 2-exo-monooxygenase, 15 LO 2, 15-LOX-2, 15-LOX-B, 15-lipoxygenase 2, AI413597, AW045860, Albendazole monooxygenase, Albendazole sulfoxidase, Alox15b, Antigen NY-CO-13, Arachidonate 15 lipoxygenase second type, Arachidonate 15-lipoxygenase B, Arachidonate 15-lipoxygenase type II, BCC7, CP33, CP34, CP3A4_HUMAN, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIIA3, CYPIIIA4, Cellular tumor antigen p53, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450-PCN1, DDPAC, ERK-2, ERT1, Extracellular signal-regulated kinase 2, FLJ31424, FLJ92943, FTDP 17, G protein beta1/gamma2 subunit interacting factor 1, Glucocorticoid inducible P450, HAP, HBV-activated protein, HLP, LFS1, LX15B_HUMAN, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPT, MAPTL, MGC126680, MGC134287, MGC138549, MGC156663, MK01_HUMAN, MSTD, MTBT1, MTBT2, Microtubule associated protein tau isoform 4, Microtubule-associated protein tau, Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, Mtapt, Mutant tumor protein 53, NF 25, NR1B1, NR1B2, NR1B3, Neurofibrillary tangle protein, Nifedipine oxidase, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, Nuclear receptor subfamily 1 group B member 1, Nuclear receptor subfamily 1 group B member 2, Nuclear receptor subfamily 1 group B member 3, Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, P38, P41, P450 III steroid inducible, P450 PCN1, P450, family III, P450C3, P53_HUMAN, PHF-tau, PPND, PPP1R103, PRKM 2, PRKM1, Paired helical filament-tau, Phosphoprotein p53, Protein phosphatase 1, regulatory subunit 103, Quinine 3-monooxygenase, RAR, RAR-alpha, RAR-beta, RAR-epsilon, RAR-gamma, RARA_HUMAN, RARB_HUMAN, RARC, RARG_HUMAN, RARalpha1, RNPTAU, RRB2, Retinoic acid nuclear receptor alpha variant 1, Retinoic acid nuclear receptor alpha variant 2, Retinoic acid receptor alpha, Retinoic acid receptor alpha polypeptide, Retinoic acid receptor beta, Retinoic acid receptor beta 2, Retinoic acid receptor beta 4, Retinoic acid receptor beta 5, Retinoic acid receptor beta polypeptide, Retinoic acid receptor gamma 2, Retinoic acid receptor, gamma, TAU_HUMAN, TRP53, Tauopathy and respiratory failure, Tauopathy and respiratory failure, included, Taurochenodeoxycholate 6-alpha-hydroxylase, Tp53, Transformation related protein 53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, p42-MAPK, p53 tumor suppressor, pTau, protein kinase, mitogen-activated, 1, protein kinase, mitogen-activated, 2, protein tyrosine kinase ERK2, tumor antigen p55