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AB141924

Cytarabine, Pyrimidine nucleoside analog

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(1 출판물)

MW 243.22 Da, Purity >99%. Pyrimidine nucleoside analog able to inhibits DNA synthesis. Active specifically on the S phase of the cell cycle. Chemotherapeutic agent. Antiviral and immunosuppressant properties.

대체 명칭 보기

ACTR, AI838772, AIB-1, AIS, ANDR_HUMAN, AR, AR8, AW493413, Amplified in breast cancer 1, Amplified in breast cancer 1 protein, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor, testicular feminization, spinal and bulbar muscular atrophy, Kennedy disease), Antigen NY-CO-13, BCC7, CAGH 16, CAR, CAR BETA, CARA, CBP-interacting protein, CTG 26, Car 1, Cellular tumor antigen p53, Class E basic helix-loop-helix protein 42, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, DHTR, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), EC 2.1.1.45, FLJ11090, FLJ92943, HUMARA, HYSP1, HsT422, IMD42, KAT13B / AIB1, KD, Kennedy disease (KD), LFS1, MB67, MGC104252, MGC112732, MGC129539, MGC141848, MGC88736, MGC97144, Mutant tumor protein 53, NCOA3_HUMAN, NR1F3, NR1I3_HUMAN, NR3C4, Nuclear receptor ROR-gamma, Nuclear receptor RZR-gamma, Nuclear receptor coactivator 3, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor subfamily 1 group I member 3, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), OTTHUMP00000162195, Orphan nuclear receptor MB67, Orphan nuclear receptor NR1I3, P53_HUMAN, Phosphoprotein p53, RAR related orphan nuclear receptor variant 2, RAR related orphan receptor C, isoform a, RAR related orphan receptor gamma, RAR-related orphan receptor C, RORG_HUMAN, RP24-311F12.2, RZR GAMMA, RZRG, Receptor-associated coactivator 3, Retinoic acid binding receptor gamma, Retinoid-related orphan receptor-gamma, Rorc, SBMA, SCAN1, SMAX1, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), Steroid receptor coactivator protein 3, TFM, TMS, TNRC 14, TNRC16, TOR, TRP53, TS, TSase, TYDP, TYDP1_HUMAN, TYMS protein, TYSY_HUMAN, Testicular Feminization (TFM), Thymidylate synthase, Thymidylate synthetase, Thyroid hormone receptor activator molecule 1, Tp53, Transformation related protein 53, Tumor protein 53, Tumor protein p53, Tumor suppressor p53, Tyms, Tyms thymidylate synthetase, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, androgen receptor splice variant 4b, bHLHe42, constitutive active receptor, constitutive androstane nuclear receptor variant 2, constitutive androstane nuclear receptor variant 3, constitutive androstane nuclear receptor variant 4, constitutive androstane nuclear receptor variant 5, d TMP synthase, orphan nuclear hormone receptor, p53 tumor suppressor, pCIP, tumor antigen p55

1 이미지
Chemical Structure - Cytarabine, Pyrimidine nucleoside analog (AB141924)
  • Chemical Structure

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Chemical Structure - Cytarabine, Pyrimidine nucleoside analog (AB141924)

2D chemical structure image of ab141924, Cytarabine, Pyrimidine nucleoside analog

주요 정보

CAS 번호

147-94-4

Purity

>99%

제형

Solid

form

Molecular weight

243.22 Da

Molecular formula

C<sub>9</sub>H<sub>1</sub><sub>3</sub>N<sub>3</sub>O<sub>5</sub>

PubChem

6253

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Soluble in DMSO to 50 mM

생화학적 명칭

Cytarabine

생물학적 정보

Pyrimidine nucleoside analog able to inhibits DNA synthesis. Active specifically on the S phase of the cell cycle. Chemotherapeutic agent. Antiviral and immunosuppressant properties.

Canonical SMILES

C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

Isomeric SMILES

C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O

InChi

InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

InChiKey

UHDGCWIWMRVCDJ-CCXZUQQUSA-N

IUPAC Name

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
Ambient
적절한 장기 보관 조건
Ambient
보관 정보
The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Toxic, refer to SDS for further information.

제품 프로토콜

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in cellular neuroscience 12:44 PubMed29556177

2018

An Easy-to-Implement Protocol for Preparing Postnatal Ventral Mesencephalic Cultures.

Applications

Unspecified application

Species

Unspecified reactive species

Janin Lautenschläger,Eugene V Mosharov,Ellen Kanter,David Sulzer,Gabriele S Kaminski Schierle
제품이 사용된 논문 모두 보기

Product promise

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