Dihydroartemisinin, active metabolite of artemether and artesunate

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MW 284.35 Da. Induces cell cycle arrest and inhibits cell migration in cancer cells. Depletes cellular iron via transferrin receptor 1. Antimalarial and antitumor agent. Orally active. Active in vivo and in vitro.

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AI838772, AIS, ANDR_HUMAN, AR, AR8, AW493413, Androgen nuclear receptor variant 2, Androgen receptor, Androgen receptor (dihydrotestosterone receptor, testicular feminization, spinal and bulbar muscular atrophy, Kennedy disease), Atherosclerosis, susceptibility to, included, DHTR, DKFZp686N23123, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), ER, ER-alpha, ER-beta, ER[a], ER[b], ESR, ESR B, ESR BETA, ESR1_HUMAN, ESRA, ESTR B, Era, Erb, Erb2, Estr, Estra, Estradiol Receptor alpha, Estradiol Receptor beta, Estradiol receptor, Estrogen Receptor 1, Estrogen Receptor 2, Estrogen receptor, Estrogen receptor 1 (alpha), Estrogen receptor 2 (ER beta), Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor beta 4, Estrogen resistance, included, FLJ11090, HDL cholesterol, augmented response of, to hormone replacement, included, HUMARA, HYSP1, KD, Kennedy disease (KD), MGC104252, MGC112732, Myocardial infarction, susceptibility to, included, NR3A1, NR3A2, NR3C4, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, Nuclear receptor subfamily 3 group C member 4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR, RP24-311F12.2, SBMA, SCAN1, SMAX1, Spinal and bulbar muscular atrophy, Spinal and bulbar muscular atrophy (SBMA), TFM, TYDP, TYDP1_HUMAN, Testicular Feminization (TFM), Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, androgen receptor splice variant 4b