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AB141390

Dithiothreitol (DTT), reducing reagent

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Dithiothreitol (DTT) (ab141390) is a cell-permeable reducing reagent. Prevents oxidation of thiol groups. Protective and protein purification agent. MW: 154.3, Purity >99%.

- Supplied as 1M in H2O solution
- Can be used to make Laemmli SDS protein sample loading buffer for SDS-PAGE
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Chemical Structure - Dithiothreitol (DTT), reducing reagent (AB141390)
  • Chemical Structure

Lab

Chemical Structure - Dithiothreitol (DTT), reducing reagent (AB141390)

2D chemical structure image of ab141390, Dithiothreitol (DTT), reducing reagent

주요 정보

CAS 번호

3483-12-3

Purity

>99%

제형

Liquid

form

Formulation

pH: 3 - 5 Constituents: 85% Water, 15% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

Molecular weight

154.3 Da

Molecular formula

C<sub>4</sub>H<sub>1</sub><sub>0</sub>O<sub>2</sub>S<sub>2</sub>

PubChem

446094

Nature

Synthetic

생화학적 명칭

D-1,4-Dithiothreitol

생물학적 정보

Cell-permeable reducing reagent. Prevents oxidation of thiol groups. Protective and protein purification agent. Active in vivo and in vitro.

Canonical SMILES

C(C(C(CS)O)O)S

Isomeric SMILES

C([C@H]([C@@H](CS)O)O)S

InChi

InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1

InChiKey

VHJLVAABSRFDPM-QWWZWVQMSA-N

IUPAC Name

(2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol

Concentration

1 M

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보완 제품

Secondary Antibodies

AB205718

Goat Anti-Rabbit IgG H&L (HRP)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Goat Anti-Rabbit IgG H&L (HRP) (AB205718)

  • 5
  • 8
Reagents, Controls & Accessories

AB288006

RIPA Buffer

  • 0
  • 0
Multiplex Kits

AB65621

Protease Inhibitor Cocktail

  • 0
  • 0
Multiplex Kits

AB201112

Phosphatase Inhibitor Cocktail I

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  • 0
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제품 세부 정보

This product is manufactured by BioVision, an Abcam company and was previously called 1201 DTT. 1201-1 is the same size as the 1 ML size of ab141390.

Supplied in water (1 M).

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특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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제품 프로토콜

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록and refine your search

Cell reports 43:114406 PubMed38963759

2024

ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yuting Lu,Jana Travnickova,Mihaly Badonyi,Florian Rambow,Andrea Coates,Zaid Khan,Jair Marques,Laura C Murphy,Pablo Garcia-Martinez,Richard Marais,Pakavarin Louphrasitthiphol,Alex H Y Chan,Christopher J Schofield,Alex von Kriegsheim,Joseph A Marsh,Valeria Pavet,Owen J Sansom,Robert S Illingworth,E Elizabeth Patton
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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