Indoximod, Indoleamine 2,3-dioxygenase (IDO) inhibitor

주요 정보

CAS 번호

110117-83-4

Purity

>95%

제형

Solid

form

Molecular weight

218.25 Da

Molecular formula

C₁₂H₁₄N₂O₂

PubChem

405012

Nature

Synthetic

생화학적 명칭

Indoximod

생물학적 정보

Methylated tryptophan which acts as an Indoleamine 2,3-dioxygenase (IDO) inhibitor. Prevents T-cell anergy triggered by dendritic cells overexpressing IDO in mice.

Canonical SMILES

CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N

Isomeric SMILES

CN1C=C(C2=CC=CC=C21)C[C@H](C(=O)O)N

InChi

InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1

InChiKey

ZADWXFSZEAPBJS-SNVBAGLBSA-N

IUPAC Name

(2R)-2-amino-3-(1-methylindol-3-yl)propanoic acid