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AB142802

ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator

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(5 제품이 사용된 논문 )

ION NaTRIUM Green™-2 AM (ING-2 AM) (CAS: 1642554-49-1) (ab142802) is a cell-permeable fluorescent Na+ indicator. Binds to sodium (Kd = 20 mM) and displays excitation/emission maxima of 525 and 545 nm, respectively. MW 1083.9.

- Larger volume format available upon request
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Chemical Structure - ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator (AB142802)
  • Chemical Structure

Lab

Chemical Structure - ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator (AB142802)

2D chemical structure image of ab142802, ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator

주요 정보

CAS 번호

1642554-49-1

제형

Solid

form

Molecular weight

1083.9 Da

Molecular formula

C<sub>5</sub><sub>3</sub>H<sub>6</sub><sub>0</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>1</sub><sub>8</sub>

PubChem

163341954

Nature

Synthetic

Solubility

Soluble in DMSO to 1mg/ml

생화학적 명칭

Asante NaTRIUM Green-2 AM

Canonical SMILES

CC1=CC(=C(C=C1)N2CCOCCN(CCOCCOCC2)C3=C(C=C(C=C3)C4=C5C=C(C(=O)C(=C5OC6=C4C=C(C(=C6Cl)OCOC(=O)C)CCC(=O)OCOC(=O)C)Cl)CCC(=O)OCOC(=O)C)OC)OC

InChi

InChI=1S/C53H60Cl2N2O18/c1-32-7-11-41(43(25-32)64-5)56-15-19-66-20-16-57(18-22-68-24-23-67-21-17-56)42-12-8-36(28-44(42)65-6)47-39-26-37(9-13-45(61)72-29-69-33(2)58)50(63)48(54)52(39)75-53-40(47)27-38(10-14-46(62)73-30-70-34(3)59)51(49(53)55)74-31-71-35(4)60/h7-8,11-12,25-28H,9-10,13-24,29-31H2,1-6H3

IUPAC Name

acetyloxymethyl 3-[3-(acetyloxymethoxy)-7-[3-(acetyloxymethoxy)-3-oxopropyl]-4,5-dichloro-9-[3-methoxy-4-[13-(2-methoxy-4-methylphenyl)-1,4,10-trioxa-7,13-diazacyclopentadec-7-yl]phenyl]-6-oxoxanthen-2-yl]propanoate

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보완 제품

Secondary Antibodies

AB205718

Goat Anti-Rabbit IgG H&L (HRP)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Goat Anti-Rabbit IgG H&L (HRP) (AB205718)

  • 5
  • 8
Primary Antibodies

AB181602

Anti-GAPDH antibody [EPR16891] - Loading Control

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GAPDH antibody [EPR16891] - Loading Control (AB181602)

  • 5
  • 23
Biochemicals

AB142800

SBFI AM, fluorescent Na+ indicator

Chemical Structure - SBFI AM, fluorescent Na+ indicator (AB142800)

  • 0
  • 0
Biochemicals

AB142806

ION Potassium Green-2 AM, K+ indicator

Chemical Structure - ION Potassium Green-2 AM, K+ indicator (AB142806)

  • 0
  • 0
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제품 세부 정보

Affinity is 20 mM/34 mM Kd for sodium (absence/presence of K+), and 39 mM (in astrocytes).

Check out our range of Na+ indicator biochemicals here
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특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Store under desiccating conditions|The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

|For more information on AM esters, please visit our

product support page.

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제품 프로토콜

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제품이 사용된 논문 (5)

Recent publications for all applications. Explore the 전체 목록 and refine your search

PloS one 16:e0250095 PubMed33891591

2021

Impact of Na+ permeation on collective migration of pulmonary arterial endothelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Ningyong Xu,Linn Ayers,Viktoriya Pastukh,Mikhail Alexeyev,Troy Stevens,Dhananjay T Tambe

Science advances 7: PubMed33523987

2021

The nuclear piston activates mechanosensitive ion channels to generate cell migration paths in confining microenvironments.

Applications

Unspecified application

Species

Unspecified reactive species

Hong-Pyo Lee,Farid Alisafaei,Kolade Adebawale,Julie Chang,Vivek B Shenoy,Ovijit Chaudhuri

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 54:556-566 PubMed32462850

2020

Fluorometric Na Evaluation in Single Cells Using Flow Cytometry: Comparison with Flame Emission Assay.

Applications

Flow Cyt

Species

Unspecified reactive species

Valentina E Yurinskaya,Nikolay D Aksenov,Alexey V Moshkov,Tatyana S Goryachaya,Alexey A Vereninov

Cancer cell 35:767-781.e6 PubMed31085177

2019

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.

Applications

Unspecified application

Species

Unspecified reactive species

Mercedes Segovia,Sofia Russo,Mathias Jeldres,Yamil D Mahmoud,Valentina Perez,Maite Duhalde,Pierre Charnet,Matthieu Rousset,Sabina Victoria,Florencia Veigas,Cédric Louvet,Bernard Vanhove,R Andrés Floto,Ignacio Anegon,Maria Cristina Cuturi,M Romina Girotti,Gabriel A Rabinovich,Marcelo Hill

PloS one 14:e0213751 PubMed30856233

2019

Development of a high-throughput fluorescent no-wash sodium influx assay.

Applications

Unspecified application

Species

Unspecified reactive species

Bryan Tay,Teneale A Stewart,Felicity M Davis,Jennifer R Deuis,Irina Vetter
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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