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AB120256

Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist

5

(1 리뷰)

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(15 제품이 사용된 논문 )

MW 211.15 Da, Purity >99%. Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo.

대체 명칭 보기

GLUR, Smp_128940

1 이미지
Chemical Structure - Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist (AB120256)
  • Chemical Structure

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Chemical Structure - Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist (AB120256)

2D chemical structure image of ab120256, Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist

주요 정보

CAS 번호

2439-02-3

Purity

>99%

제형

Solid

form

Molecular weight

211.15 Da

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>6</sub>NNaO<sub>3</sub>

PubChem

52974250

Nature

Synthetic

생화학적 명칭

Kynurenic acid sodium salt

생물학적 정보

Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo.

Canonical SMILES

C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)[O-].[Na+]

InChi

InChI=1S/C10H7NO3.Na/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9;/h1-5H,(H,11,12)(H,13,14);/q;+1/p-1

InChiKey

RCAZGXKUQDXSSK-UHFFFAOYSA-M

IUPAC Name

sodium;4-oxo-1H-quinoline-2-carboxylate

특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
Ambient
적절한 장기 보관 조건
Ambient
보관 정보
Store under desiccating conditions|The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

제품 프로토콜

제품이 사용된 논문 (15)

Recent publications for all applications. Explore the 전체 목록 and refine your search

iScience 25:105467 PubMed36388998

2022

Conformational state-dependent regulation of GABA receptor diffusion and subsynaptic domains.

Applications

Unspecified application

Species

Unspecified reactive species

Zaha Merlaud,Xavier Marques,Marion Russeau,Ursula Saade,Maelys Tostain,Imane Moutkine,Marc Gielen,Pierre-Jean Corringer,Sabine Lévi

Cell metabolism 34:1532-1547.e6 PubMed36198294

2022

Hypothalamic astrocytes control systemic glucose metabolism and energy balance.

Applications

Unspecified application

Species

Unspecified reactive species

Daniela Herrera Moro Chao,Matthew K Kirchner,Cuong Pham,Ewout Foppen,Raphael G P Denis,Julien Castel,Chloe Morel,Enrica Montalban,Rim Hassouna,Linh-Chi Bui,Justine Renault,Christine Mouffle,Cristina García-Cáceres,Matthias H Tschöp,Dongdong Li,Claire Martin,Javier E Stern,Serge H Luquet

Neuron 110:841-856.e6 PubMed34982958

2022

Make war not love: The neural substrate underlying a state-dependent switch in female social behavior.

Applications

Unspecified application

Species

Unspecified reactive species

Mengyu Liu,Dong-Wook Kim,Hongkui Zeng,David J Anderson

Neuron 109:1721-1738.e4 PubMed33823137

2021

Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon.

Applications

Unspecified application

Species

Unspecified reactive species

Lauren E McElvain,Yuncong Chen,Jeffrey D Moore,G Stefano Brigidi,Brenda L Bloodgood,Byung Kook Lim,Rui M Costa,David Kleinfeld

Neuron 109:1365-1380.e5 PubMed33740416

2021

Periaqueductal gray/dorsal raphe dopamine neurons contribute to sex differences in pain-related behaviors.

Applications

Unspecified application

Species

Unspecified reactive species

Waylin Yu,Dipanwita Pati,Melanie M Pina,Karl T Schmidt,Kristen M Boyt,Avery C Hunker,Larry S Zweifel,Zoe A McElligott,Thomas L Kash

Cell 179:713-728.e17 PubMed31626771

2019

Multimodal Analysis of Cell Types in a Hypothalamic Node Controlling Social Behavior.

Applications

Unspecified application

Species

Unspecified reactive species

Dong-Wook Kim,Zizhen Yao,Lucas T Graybuck,Tae Kyung Kim,Thuc Nghi Nguyen,Kimberly A Smith,Olivia Fong,Lynn Yi,Noushin Koulena,Nico Pierson,Sheel Shah,Liching Lo,Allan-Hermann Pool,Yuki Oka,Lior Pachter,Long Cai,Bosiljka Tasic,Hongkui Zeng,David J Anderson

eLife 8: PubMed31364987

2019

The readily-releasable pool dynamically regulates multivesicular release.

Applications

Unspecified application

Species

Unspecified reactive species

Jada H Vaden,Gokulakrishna Banumurthy,Eugeny S Gusarevich,Linda Overstreet-Wadiche,Jacques I Wadiche

eLife 8: PubMed30883329

2019

Complementary networks of cortical somatostatin interneurons enforce layer specific control.

Applications

Unspecified application

Species

Unspecified reactive species

Alexander Naka,Julia Veit,Ben Shababo,Rebecca K Chance,Davide Risso,David Stafford,Benjamin Snyder,Andrew Egladyous,Desiree Chu,Savitha Sridharan,Daniel P Mossing,Liam Paninski,John Ngai,Hillel Adesnik

Scientific reports 7:9969 PubMed28855588

2017

Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src.

Applications

Unspecified application

Species

Unspecified reactive species

Fiona A Bull,Daniel T Baptista-Hon,Jeremy J Lambert,Wendy Walwyn,Tim G Hales

Scientific reports 7:3025 PubMed28596596

2017

Optical mapping of neuronal activity during seizures in zebrafish.

Applications

Unspecified application

Species

Unspecified reactive species

L Turrini,C Fornetto,G Marchetto,M C Müllenbroich,N Tiso,A Vettori,F Resta,A Masi,G Mannaioni,F S Pavone,F Vanzi
제품이 사용된 논문 모두 보기

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