Monosodium urate, Pro-inflammatory agent

주요 정보

CAS 번호

1198-77-2

Molecular weight

190.09 Da

Molecular formula

C₅H₃N₄NaO₃

PubChem

23697816

Nature

Synthetic

Solubility

Soluble in 1 N NaOH to 25 mM

생화학적 명칭

Sodium urate

생물학적 정보

NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.

Canonical SMILES

C12=C(NC(=O)NC1=O)[N-]C(=O)N2.[Na+]

InChi

InChI=1S/C5H4N4O3.Na/c10-3-1-2(7-4(11)6-1)8-5(12)9-3;/h(H4,6,7,8,9,10,11,12);/q;+1/p-1

InChiKey

NAFSTSRULRIERK-UHFFFAOYSA-M

IUPAC Name

sodium;3,7-dihydropurin-9-ide-2,6,8-trione