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AB120410

RuBi-4AP, Caged K+ channel blocker

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(1 출판물)

MW 672.58 g/mol. Water soluble caged 4-aminopyridine (4-AP) based on ruthenium photochemistry. Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases voltage-dependent K+ channel blocker 4-aminopyridine (ab120122) when uncaged.
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Chemical Structure - RuBi-4AP, Caged K+ channel blocker (AB120410)
  • Chemical Structure

Lab

Chemical Structure - RuBi-4AP, Caged K+ channel blocker (AB120410)

2D chemical structure image of ab120410, RuBi-4AP, Caged K+ channel blocker

주요 정보

CAS 번호

851956-02-0

제형

Solid

form

Molecular weight

672.58 g/mol

Nature

Synthetic

Solubility

Soluble in water

생물학적 정보

Water soluble caged 4-aminopyridine (4-AP) based on ruthenium photochemistry. Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases voltage-dependent K+ channel blocker 4-aminopyridine (ab120122) when uncaged.

IUPAC Name

Bis(2,2'-bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex

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보완 제품

Biochemicals

AB120122

4-Aminopyridine (4-AP), K+ channel blocker

Immunocytochemistry/ Immunofluorescence - 4-Aminopyridine (4-AP), K+ channel blocker (AB120122)

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Biochemicals

AB120042

SR95531 (Gabazine), GABAA antagonist

Chemical Structure - SR95531 (Gabazine), GABAA antagonist (AB120042)

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Biochemicals

AB120371

NS309, K+ channel activator

Chemical Structure - NS309, K+ channel activator (AB120371)

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Biochemicals

AB120267

Glibenclamide (Glyburide), K+ channel blocker

Functional Studies - Glibenclamide (Glyburide), K+ channel blocker (AB120267)

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제품 세부 정보

RuBi-4AP is light sensitive and it is recommended that the compound is protected from light.

Sold under license from Columbia University; Patent Pending.

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특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
It is important to note that this product is reported to be light sensitive|Store in the dark|Store under desiccating conditions
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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제품 프로토콜

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of neuroscience : the official journal of the Society for Neuroscience 34:6611-23 PubMed24806686

2014

Distinct Kv channel subtypes contribute to differences in spike signaling properties in the axon initial segment and presynaptic boutons of cerebellar interneurons.

Applications

Unspecified application

Species

Unspecified reactive species

Matthew J M Rowan,Elizabeth Tranquil,Jason M Christie
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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