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AB120563

(S)-(-)-Raclopride, D2 receptor antagonist

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(1 출판물)

MW 347.24 g/mol, Purity >97%. High affinity (Kd = 1.2 nM) and high selectivity for D2 receptors in vitro and in vivo (IC50 = 32 nM). Centrally active following systemic administration.
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Chemical Structure - (S)-(-)-Raclopride, D2 receptor antagonist (AB120563)
  • Chemical Structure

Lab

Chemical Structure - (S)-(-)-Raclopride, D2 receptor antagonist (AB120563)

2D chemical structure image of ab120563, (S)-(-)-Raclopride, D2receptor antagonist

주요 정보

CAS 번호

84225-95-6

Purity

>97%

제형

Solid

form

Molecular weight

347.24 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 25 mM

생물학적 정보

High affinity (Kd = 1.2 nM) and high selectivity for D2 receptors in vitro and in vivo (IC50 = 32 nM). Centrally active following systemic administration.

IUPAC Name

3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide

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보완 제품

Assay Kits

AB113849

Luminescent ATP Detection Assay Kit

Functional Studies (Act) - Luminescent ATP Detection Assay Kit (AB113849)

  • 5
  • 6
Assay Kits

AB212166

Human BDNF ELISA Kit

SimpleStep

ELISA - Human BDNF ELISA Kit (AB212166)

  • 4
  • 2
Primary Antibodies

AB281588

Anti-MAP2 antibody [RM1010] - Neuronal Marker

RabMAb|Recombinant|Lab Essentials|20ul selling size

Flow Cytometry (Intracellular) - Anti-MAP2 antibody [RM1010] - Neuronal Marker (AB281588)

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Primary Antibodies

AB137869

Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (AB137869)

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특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
Ambient
적절한 장기 보관 조건
Ambient
보관 정보
The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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제품 프로토콜

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell reports 42:112149 PubMed36821440

2023

Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience.

Applications

Unspecified application

Species

Unspecified reactive species

Yuma Nagai,Yuri Kisaka,Kento Nomura,Naoya Nishitani,Chihiro Andoh,Masashi Koda,Hiroyuki Kawai,Kaoru Seiriki,Kazuki Nagayasu,Atsushi Kasai,Hisashi Shirakawa,Takanobu Nakazawa,Hitoshi Hashimoto,Shuji Kaneko
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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