MW 356.4 Da, Purity >97%. Selective, non-peptide orexin receptor 1 (OX1) antagonist (Ki = 26.9 nM). Displays 50-fold selectivity over OX2 (Kb values are 21.7 and 1405 nM for OX1 and OX2, respectively).
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(R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, 1 25 dihydroxyvitamin D3 receptor, 1,8-cineole 2-exo-monooxygenase, 25-dihydroxyvitamin D3 receptor, 5 HT 2B receptor, 5 HT(2B), 5 hydroxytryptamine (serotonin) receptor 2B, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine 2B receptor, 5-hydroxytryptamine receptor 2B, 5HT2B_HUMAN, 5HT2F, Albendazole monooxygenase, Albendazole sulfoxidase, CP2C9_HUMAN, CP33, CP34, CP3A4_HUMAN, CPC12, CPC8, CPC9, CPCJ, CYP2C, CYP2C10, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIC9, CYPIIIA3, CYPIIIA4, Cytochrome P-450MP, Cytochrome P450 2C9, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 NF-25, Cytochrome P450 PB-1, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450, family 2, subfamily C, polypeptide 9, Cytochrome P450-PCN1, D(1A) dopamine receptor, D1A dopamine receptor, DADR, DRD 1A, DRD1_HUMAN, Dopamine D1 receptor, Glucocorticoid inducible P450, HCRTR 1, HLP, Hcr tr2, Hcrt receptor 2, Htr 2b, Hypocretin (orexin) receptor 2, Hypocretin receptor 2, Hypocretin receptor type 1, Hypocretin receptor type 2, MGC126680, MGC149605, MGC88320, Member 1, Microsomal monooxygenase, NF 25, NP75 protein, NR1I1, Nifedipine oxidase, Nuclear receptor subfamily 1 group I member 1, OTTHUMP00000020135, OX1R_HUMAN, OX2R_HUMAN, Orexin 2 receptor, Orexin A/Orexin B receptor, Orexin Receptor 1, Orexin receptor 2, Orexin receptor type 1, Orexin receptor type 2, Orexin type 2 receptor, P450 III steroid inducible, P450 MP, P450 PB 1, P450 PCN1, P450, family III, P450C2C, P450C3, P450IIC19, P450IIC9, PPP1R163, Protein phosphatase 1, regulatory subunit 163, Quinine 3-monooxygenase, S-mephenytoin 4-hydroxylase, SEROTONIN 5HT2B RECEPTOR, Serotonin receptor 2B, Stomach fundus serotonin receptor, Taurochenodeoxycholate 6-alpha-hydroxylase, Type 2 hypocretin receptor, Type 2 orexin receptor, VDR_HUMAN, Vitamin D (1,25- dihydroxyvitamin D3) receptor, Vitamin D hormone receptor, Vitamin D nuclear receptor variant 1, Vitamin D receptor, Vitamin D3 receptor, Xenobiotic monooxygenase, cytochrome P-450 S-mephenytoin 4-hydroxylase, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, dopamine receptor D1, flavoprotein-linked monooxygenase
- Chemical Structure
Lab
Chemical Structure - SB 408124, non-peptide OX1 antagonist (AB141105)
2D chemical structure image of ab141105, SB 408124, non-peptide OX1 antagonist
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