AB120163

SB431542, ALK inhibitor

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SB431542, ALK inhibitor (CAS: 301836-41-9)(ab120163) is a potent and selective inhibitor of Activin receptor-like kinase (ALK). Molecular weight of SB431542 is 384.4 g/mol.

- Inhibits ALK 4, 5 (IC₅₀ = 94 nM), and 7
- Available in different formats to fit your experimental needs. Larger volume format available upon request

1 이미지

Chemical Structure - SB431542, ALK inhibitor (AB120163)

Chemical Structure

Lab

Chemical Structure - SB431542, ALK inhibitor (AB120163)

2D chemical structure image of ab120163, SB431542, ALK inhibitor

주요 정보

CAS 번호

301836-41-9

Purity

>99%

제형

Solid

form

Formulation

Constituents: 100% SB431542

Molecular weight

384.4 Da

Molecular formula

C22H16N4O3

PubChem

4521392

Nature

Synthetic

생화학적 명칭

4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide

생물학적 정보

Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC₅₀ = 94 nM), and 7.

Canonical SMILES

C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5

InChi

InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)

InChiKey

FHYUGAJXYORMHI-UHFFFAOYSA-N

IUPAC Name

4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide

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제품 세부 정보

SB431542, ALK inhibitor (ab120163) is a potent and selective inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors 4, 5 and 7.

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특성 및 보관 정보

배송 시 보관 조건

Ambient - Can Ship with Ice

적절한 단기 보관 조건

Ambient

적절한 장기 보관 조건

Ambient

보관 정보

Store under desiccating conditions|The product can be stored for up to 12 months

취급 방법

Need more advice on solubility, usage and handling? Please visit our product support page for more details.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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제품 프로토콜

Visit the General protocols
Visit the Troubleshooting

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제품이 사용된 논문 (51)

Recent publications for all applications. Explore the 전체 목록and refine your search

Theranostics 15:7127-7153 PubMed40585989

2025

FAK signaling suppression by OCT4-ITGA6 mediates the effectively removal of residual pluripotent stem cells and enhances application safety.

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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11:e2304987 PubMed37991133

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Automated, High-Throughput Phenotypic Screening and Analysis Platform to Study Pre- and Post-Implantation Morphogenesis in Stem Cell-Derived Embryo-Like Structures.

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Nature methods 20:1388-1399 PubMed37474806

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Efficient high-precision homology-directed repair-dependent genome editing by HDRobust.

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SB431542, ALK inhibitor

Chemical Structure - SB431542, ALK inhibitor (AB120163)

주요 정보

CAS 번호

Purity

제형

Formulation

Molecular weight

Molecular formula

PubChem

Nature

생화학적 명칭

생물학적 정보

Canonical SMILES

InChi

InChiKey

IUPAC Name

보완 제품

Biochemicals

Biochemicals

Primary Antibodies

Primary Antibodies

제품 세부 정보

특성 및 보관 정보

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

보관 정보

취급 방법

제품 프로토콜

제품이 사용된 논문 (51)

Product promise