SB431542 (DMSO solution), ALK inhibitor
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(2 제품이 사용된 논문 )
SB431542 (CAS: 301836-41-9) (ab146590) is a ALK inhibitor in DMSO solution. Potent and selective inhibitor of Activin Like Kinase (ALK). Inhibits ALK 4, 5 (IC50 = 94 nM), and 7. TGF-β receptor kinase inhibitor (TRKI). MW 384.4.
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대체 명칭 보기
AAT 5, ACTR-IB, ACTR-IC, ACV1B_HUMAN, ACV1C_HUMAN, ACVR 1B, ACVRLK 4, ACVRLK7, ALK-4, ALK-5, ALK-7, Activin A receptor type 1B, Activin A receptor type II like kinase, Activin A receptor type II like kinase 4, Activin A receptor type II like kinase 53kDa, Activin A receptor type II like kinase, 53kD, Activin A receptor, type IC, Activin A type 1B receptor, Activin A type IB receptor, Activin receptor type 1C precursor, Activin receptor type IB, Activin receptor type IC, Activin receptor type-1B, Activin receptor type-1C, Activin receptor-like kinase 4, Activin receptor-like kinase 5, Activin receptor-like kinase 7, Acvr1c, LDS1A, LDS2A, MSSE, SKR 2, SKR 4, Serine(threonine) protein kinase receptor R2, Serine/threonine-protein kinase receptor R2, Serine/threonine-protein kinase receptor R4, TGF-beta receptor type I, TGF-beta receptor type-1, TGF-beta type I receptor, TGFBR 1, TGFBR1 protein, TGFR1_HUMAN, TbetaR-I, Transforming growth factor beta receptor 1, Transforming growth factor beta receptor I, Transforming growth factor beta receptor I (activin A receptor type II like kinase, 53kD), Transforming growth factor-beta receptor type I, activin A receptor type II-like protein kinase of 53kD
- Chemical Structure
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Chemical Structure - SB431542 (DMSO solution), ALK inhibitor (AB146590)
2D chemical structure image of ab146590, SB431542 (DMSO solution), ALK inhibitor
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Need more advice on solubility, usage and handling? Please visit our our product support page for more details.
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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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Refer to SDS for further information.
제품이 사용된 논문 (2)
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Cell reports 29:2702-2717.e7 PubMed31775039
2019
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Unspecified application
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Unspecified reactive species
Developmental cell 50:462-477.e5 PubMed31204172
2019
Applications
Unspecified application
Species
Unspecified reactive species
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