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AB146579

Tetracycline hydrochloride (aqueous), antibiotic

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MW 480.9 g/mol. Broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne.

Tetracycline passively diffuses through protein channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells.

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Chemical Structure - Tetracycline hydrochloride (aqueous), antibiotic (AB146579)
  • Chemical Structure

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Chemical Structure - Tetracycline hydrochloride (aqueous), antibiotic (AB146579)

2D chemical structure image of ab146579, Tetracycline hydrochloride (aqueous), antibiotic

주요 정보

CAS 번호

64-75-5

제형

Liquid

form

Molecular weight

480.9 g/mol

Molecular formula

C<sub>2</sub><sub>2</sub>H<sub>2</sub><sub>5</sub>ClN<sub>2</sub>O<sub>8</sub>

Nature

Synthetic

생물학적 정보

Broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne.

Tetracycline passively diffuses through protein channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells.

50 mg/mL

특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Store under desiccating conditions|The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Toxic, refer to SDS for further information.

제품 프로토콜

Product promise

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