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AB146345

Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye

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(20 제품이 사용된 논문 )

Thiazolyl blue tetrazolium bromide (MTT) (CAS:298-93-1) (ab146345) membrane-permeable dye used to measure cell metabolic activity. MW 414; Purity > 98%.

- Suitable for assays to measure cell proliferation, cell viability and cytotoxicity
- Measure absorbance at OD = 590 nm
- Available in different sizes to fit your experimental needs. Larger volume format available upon request
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Functional Studies - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)
  • FuncS

PubMed

Functional Studies - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)

NaHS protects viability of HEI-OC1 cells upon gentamicin toxicity.

Gentamicin (GM) was added to the culture medium to a concentration of 0 (control), 1, 2.5 and 5 mM respectively incubated for 48 hours. Representative culture images (A) and viability measured by MTT assay (B) of HEI-OC1 cell culture after gentamicin (GM) treatment were shown.

Scale bar 100 μm. Values were represented as the mean ± SEM from three independent experiments. * P < 0.05 vs control.

(After Figure 1A & B of Dong et al).

Dong et al PLoS One. 2015; 10(8): e0136051. Reproduced under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

Chemical Structure - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)
  • Chemical Structure

Lab

Chemical Structure - Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye (AB146345)

2D chemical structure image of ab146345, Thiazolyl blue tetrazolium bromide (MTT), membrane-permeable dye

주요 정보

CAS 번호

298-93-1

Purity

>98%

제형

Solid

form

Molecular weight

414.3 Da

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>1</sub><sub>6</sub>BrN<sub>5</sub>S

PubChem

64965

Nature

Synthetic

생화학적 명칭

Thiazolyl blue

Canonical SMILES

CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

InChi

InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1

IUPAC Name

2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide

특성 및 보관 정보

배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

제품 프로토콜

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