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AB120936

Triciribine, inhibitor of Akt activation

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MW 320.31 g/mol, Purity >98%. Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.
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Chemical Structure - Triciribine, inhibitor of Akt activation (AB120936)
  • Chemical Structure

Lab

Chemical Structure - Triciribine, inhibitor of Akt activation (AB120936)

2D chemical structure image of ab120936, Triciribine, inhibitor of Akt activation

주요 정보

CAS 번호

35943-35-2

Purity

>98%

제형

Solid

form

Molecular weight

320.31 g/mol

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>6</sub>N<sub>6</sub>O<sub>4</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 75 mM

Soluble in ethanol to 10 mM

생물학적 정보

Cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation and signalling of Akt. Selective over PKC, PKA, SGK and p38 pathways. Induces cell growth arrest and apoptosis in vitro.

Isomeric SMILES

OC[C@H]1O[C@H](C(O)C1O)N1CC2C(N)NN(C)C3NCNC1C23

IUPAC Name

1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine

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보완 제품

Assay Kits

AB176660

ERK1 (phospho T202 + Y204) + ERK2 (phospho T185 + Y187) + Total ELISA Kit

SimpleStep

ELISA - ERK1 (phospho T202 + Y204) + ERK2 (phospho T185 + Y187) + Total ELISA Kit (AB176660)

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Biochemicals

AB120802

SC-66, Allosteric Akt inhibitor

Chemical Structure - SC-66, Allosteric Akt inhibitor (AB120802)

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Biochemicals

AB146428

SC79, Akt activator

Chemical Structure - SC79, Akt activator (AB146428)

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  • 0
Assay Kits

AB253299

AKT 1/2/3 pS473 + AKT 1/2/3 Total ELISA Kit

SimpleStep

Sandwich ELISA - AKT 1/2/3 pS473 + AKT 1/2/3 Total ELISA Kit (AB253299)

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특성 및 보관 정보

배송 시 보관 조건
Ambient - Can Ship with Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Store under desiccating conditions|The product can be stored for up to 12 months
취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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제품 프로토콜

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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