Vecuronium bromide, Competitive nicotinic acetylcholine receptor antagonist

주요 정보

CAS 번호

50700-72-6

제형

Solid

form

Molecular weight

637.74 g/mol

Molecular formula

C₃₄H₅₇BrN₂O₄

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 100 mM

Soluble in water to 25 mM

생물학적 정보

Competitive nicotinic acetylcholine receptor (nAChR) antagonist (IC₅₀ = 9.9 nM). Muscle relaxant. Inhibits neural response to hypoxia.

Isomeric SMILES

[BR-].C[N+]1(CCCCC1)C2C[C@H]3C4CC[C@H]5C[C@H](OC(C)=O)C(CC5(C)[C@H]4CCC3(C)C2OC(C)=O)N6CCCCC6

InChi

InChI=1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26?,27-,28-,29?,30?,31-,32?,33?,34?;/m0./s1

InChiKey

VEPSYABRBFXYIB-HDEGTDFTSA-M

IUPAC Name

1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide