AB145349

Zinpyr-1, Fluorogenic Zn2+ reporter

Be the first to review this product! 리뷰 제출

(8 제품이 사용된 논문 )

MW 823.72 g/mol, Purity >95%. Cell-permeable fluorogenic Zn²⁺ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.

1 이미지

Chemical Structure - Zinpyr-1, Fluorogenic Zn2+ reporter (AB145349)

Chemical Structure

Lab

Chemical Structure - Zinpyr-1, Fluorogenic Zn2+ reporter (AB145349)

2D chemical structure image of ab145349, Zinpyr-1, Fluorogenic Zn2+reporter

주요 정보

CAS 번호

288574-78-7

Purity

>95%

Molecular weight

823.72 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO

생물학적 정보

Cell-permeable fluorogenic Zn²⁺ reporter. 2,7-Dichlorofluorescein (ab146332) derivative. Induces positive fluorescence upon metal ion complexation. PET sensor.

Canonical SMILES

OC8C(CN(CC1CCCCN1)CC2CCCCN2)C9OC5C(CN(CC3CCCCN3)CC4CCCCN4)C(O)C(CL)CC5C7(OC(=O)C6CCCCC67)C9CC8CL

InChi

InChI=1S/C46H36Cl2N6O5/c47-39-21-37-43(34(41(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30)58-44-35(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)42(56)40(48)22-38(44)46(37)36-16-2-1-15-33(36)45(57)59-46/h1-22,55-56H,23-28H2

InChiKey

QZKKSPLNXQJQRQ-UHFFFAOYSA-N

IUPAC Name

4′,5′-Bis[bis(2-pyridylmethyl)aminomethyl]-2′,7′-dichlorofluorescein

Excitation/Emission

Ex: 515nm, Em: 515nm

style

left-column

style

left-column

style

left-column

특성 및 보관 정보

배송 시 보관 조건

Ambient - Can Ship with Ice

적절한 단기 보관 조건

-20°C

적절한 장기 보관 조건

-20°C

보관 정보

Store under desiccating conditions|The product can be stored for up to 12 months

취급 방법

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

style

left-column

style

left-column

제품 프로토콜

Visit the General protocols
Visit the Troubleshooting

style

left-column

제품이 사용된 논문 (8)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Life science alliance 8: PubMed39578074

2024

Membrane transporters modulating the toxicity of arsenic, cadmium, and mercury in human cells.

Applications

Unspecified application

Species

Unspecified reactive species

Andrè Ferdigg,Ann-Katrin Hopp,Gernot Wolf,Giulio Superti-Furga

BMC plant biology 23:20 PubMed36627574

2023

The auxin signaling pathway contributes to phosphorus-mediated zinc homeostasis in maize.

Applications

Unspecified application

Species

Unspecified reactive species

Zhonghua Wang,Yafei Wang,Qingguo Du,Pengshuai Yan,Baogang Yu,Wen-Xue Li,Chun-Qin Zou

BMC neuroscience 23:66 PubMed36384553

2022

Albumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn-dependent matrix metalloproteinase 9 during the early development.

Applications

Unspecified application

Species

Unspecified reactive species

Kan Zhang,Ruijing Ma,Luping Feng,Peiwen Liu,Shuang Cai,Chaoyang Tong,Jijian Zheng

Nature communications 13:6374 PubMed36289215

2022

Myocardial TRPC6-mediated Zn influx induces beneficial positive inotropy through β-adrenoceptors.

Applications

Unspecified application

Species

Unspecified reactive species

Sayaka Oda,Kazuhiro Nishiyama,Yuka Furumoto,Yohei Yamaguchi,Akiyuki Nishimura,Xiaokang Tang,Yuri Kato,Takuro Numaga-Tomita,Toshiyuki Kaneko,Supachoke Mangmool,Takuya Kuroda,Reishin Okubo,Makoto Sanbo,Masumi Hirabayashi,Yoji Sato,Yasuaki Nakagawa,Koichiro Kuwahara,Ryu Nagata,Gentaro Iribe,Yasuo Mori,Motohiro Nishida

Scientific reports 9:10471 PubMed31320712

2019

The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Moskovskich,Ulrich Goldmann,Felix Kartnig,Sabrina Lindinger,Justyna Konecka,Giuseppe Fiume,Enrico Girardi,Giulio Superti-Furga

The New phytologist 224:202-215 PubMed31131881

2019

Cytokinin-dependent regulatory module underlies the maintenance of zinc nutrition in rice.

Applications

Unspecified application

Species

Unspecified reactive species

Shaopei Gao,Yunhua Xiao,Fan Xu,Xiaokai Gao,Shouyun Cao,Fengxia Zhang,Guodong Wang,Dale Sanders,Chengcai Chu

Journal of neuroscience methods 315:14-16 PubMed30599147

2018

Perfusion alters free zinc levels in the rodent brain.

Applications

Unspecified application

Species

Unspecified reactive species

S L P Lippi,K M Craven,C M Hernandez,G M Grant,J M Flinn

Frontiers in aging neuroscience 10:382 PubMed30524268

2018

A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology.

Applications

Unspecified application

Species

Unspecified reactive species

Stephen L P Lippi,Meghann L Smith,Jane M Flinn

제품이 사용된 논문 모두 보기

style

left-column

style

left-column

style

right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Zinpyr-1, Fluorogenic Zn2+ reporter

Chemical Structure - Zinpyr-1, Fluorogenic Zn2+ reporter (AB145349)

주요 정보

CAS 번호

Purity

Molecular weight

Nature

Solubility

생물학적 정보

Canonical SMILES

InChi

InChiKey

IUPAC Name

Excitation/Emission

보완 제품

Assay Kits

Primary Antibodies

Primary Antibodies

Assay Kits

특성 및 보관 정보

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

보관 정보

취급 방법

제품 프로토콜

제품이 사용된 논문 (8)

Product promise