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AB108668

17 OH Progesterone ELISA Kit

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17 OH Progesterone ELISA Kit is a competitive ELISA designed to quantify 17 OH Progesterone with a sensitivity of 0.05 ng/mL

- Colorimetric competitive ELISA - 450 nm readout - works on any plate reader
- Suitable for serum and plasma
1 이미지
Competitive ELISA - 17 OH Progesterone ELISA Kit (AB108668)
  • cELISA

Unknown

Competitive ELISA - 17 OH Progesterone ELISA Kit (AB108668)

Representative Standard Curve using ab108668

주요 정보

검출 방식

Colorimetric

샘플 타입

Citrate plasma, Heparin Plasma, Serum

분석 유형

Competitive

Sensitivity

= 0.05 ng/mL

분석 플랫폼

Microplate

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보완 제품

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "cELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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제품 세부 정보

Abcam's 17 OH Progesterone in vitro competitive ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the accurate quantitative measurement of 17 OH Progesterone in serum and plasma.

A 96-well plate has been precoated with anti-17 OH Progesterone IgG. Samples and the 17 OH Progesterone-HRP conjugate are added to the wells, where 17 OH Progesterone in the sample competes with the added 17 OH Progesterone-HRP for antibody binding. After incubation, the wells are washed to remove unbound material and TMB substrate is then added which is catalyzed by HRP to produce blue coloration. The reaction is terminated by addition of Stop Solution which stops the color development and produces a color change from blue to yellow. The intensity of signal is inversely proportional to the amount of 17 OH Progesterone in the sample and the intensity is measured at 450 nm.

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Precision

[ { "reproducibilityType": "Intra", "sample": "Serum", "replicates": 3, "mean": null, "standardDeviation": null, "coefficientOfVariability": "<= 8.2" }, { "reproducibilityType": "Inter", "sample": "Serum", "replicates": 3, "mean": null, "standardDeviation": null, "coefficientOfVariability": "<= 13.8" } ]
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제품 구성

{ "values": { "1x96Tests": { "sellingSize": "1 x 96 Tests", "publicAssetCode":"ab108668-1x96Tests", "assetComponentDetails": [ { "size":"1 x 1 mL", "name":"17 OH Progesterone Control B", "number":"AB108668-CMP15", "productcode":"" }, { "size":"1 x 22 mL", "name":"17 OH Progesterone-HRP Conjugate", "number":"AB108668-CMP06", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Strip holder", "number":"AB108668-CMP03", "productcode":"" }, { "size":"1 x 1 mL", "name":"17 OH Progesterone Standard 1 – 0.2 ng/mL", "number":"AB108668-CMP08", "productcode":"" }, { "size":"1 x 1 mL", "name":"17 OH Progesterone Standard 5 – 16.0 ng/mL", "number":"AB108668-CMP12", "productcode":"" }, { "size":"1 x 1 mL", "name":"17 OH Progesterone Standard 2 – 0.6 ng/mL", "number":"AB108668-CMP09", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Anti-17 OH Progesterone IgG Coated Microplate (12 x 8 wells)", "number":"AB108668-CMP01", "productcode":"" }, { "size":"1 x 50 mL", "name":"10X Wash Solution", "number":"AB108668-CMP13", "productcode":"" }, { "size":"1 x 1 mL", "name":"17 OH Progesterone Standard 3 – 2.0 ng/mL", "number":"AB108668-CMP10", "productcode":"" }, { "size":"1 x 15 mL", "name":"Stop Solution", "number":"AB108668-CMP14", "productcode":"" }, { "size":"1 x 1 mL", "name":"17 OH Progesterone Control A", "number":"AB108668-CMP02", "productcode":"" }, { "size":"1 x 1 mL", "name":"17 OH Progesterone Standard 0 – 0 ng/mL", "number":"AB108668-CMP07", "productcode":"" }, { "size":"1 x 1 mL", "name":"17 OH Progesterone Standard 4 – 6.0 ng/mL", "number":"AB108668-CMP11", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Cover foils", "number":"AB108668-CMP04", "productcode":"" }, { "size":"1 x 15 mL", "name":"TMB Substrate Solution", "number":"AB108668-CMP05", "productcode":"" } ] } } }
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특성 및 보관 정보

배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Progesterone 17 Alpha OH also known as 17-hydroxyprogesterone or 17 OH progesterone is a naturally occurring steroid hormone. The target has a molecular mass of approximately 330 Da. It is mainly expressed in the adrenal glands ovaries testes and placenta. The molecule forms as an intermediate in the production of glucocorticoids and sex steroids playing a critical role in the steroidogenesis pathway. ELISA clinics often utilize it to quantify levels in samples.
Biological function summary

17 OH progesterone serves as an essential precursor in the synthesis of cortisol and androgens. This steroid operates principally in the adrenal cortex but can also affect peripheral tissues. As part of complex steroid metabolic processes it supports the body's ability to generate hormones that are fundamental for stress responses immune function and electrolyte balance. Among other hepatically-side functions it also fuels processes for forming various other hormones.

Pathways

17 OH progesterone is vital to the steroidogenesis and metabolic pathways. Steroidogenesis involves cholesterol conversion into steroid hormones where 17 OH progesterone takes part as a significant player. This conversion process requires enzymes such as 21-hydroxylase and 11β-hydroxylase influencing outputs such as cortisol and aldosterone production. The association of 17 OH progesterone with these enzymes helps maintain proper cortisol levels which is important for homeostasis.

17 OH progesterone links to congenital adrenal hyperplasia (CAH) and polycystic ovary syndrome (PCOS). Both conditions frequently involve hormonal imbalances that affect physiological functions. Deficiencies or overactivities in enzymes like 21-hydroxylase can elevate 17 OH progesterone levels leading to CAH. This increased level often results in problems like virilization and electrolyte imbalances. In PCOS altered levels may connect to the dysregulation of androgens complicating menstrual cycles and fertility.
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제품 프로토콜

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타겟 정보

See full target information Progesterone 17 Alpha OH
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of molecular sciences 17: PubMed27136540

2016

Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development.

Applications

Unspecified application

Species

Unspecified reactive species

Qiang Fu,Yulin Huang,Zhiqiang Wang,Fumei Chen,Delun Huang,Yangqing Lu,Xianwei Liang,Ming Zhang
제품이 사용된 논문 모두 보기
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websiteProtocolBooklet
en
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Product promise

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