JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB314828

Human Cathepsin X ELISA Kit

Be the first to review this product! 리뷰 제출

|

(0 출판물)

Human Cathepsin X ELISA Kit is a Sandwich ELISA for the measurement of Human Cathepsin X in Human in Biofluids, Cell Culture Media samples.

대체 명칭 보기

Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ

1 이미지
Sandwich ELISA - Human Cathepsin X ELISA Kit (AB314828)
  • sELISA

Supplier Data

Sandwich ELISA - Human Cathepsin X ELISA Kit (AB314828)

Example of standard curve using ab314828. This standard curve is for demonstrative purposes only. A standard curve must be run with each assay.

주요 정보

검출 방식

Colorimetric

샘플 타입

Serum, Plasma, Cell culture supernatant

Reacts with

Human

분석 유형

Sandwich

결과 유형

Quantitative

Sensitivity

= 1.5 pg/mL

검출 범위

1.5 - 400 pg/mL

분석 플랫폼

Pre-coated microplate (12 x 8 well strips)

style
left-column

보완 제품

Assay Kits

AB309433

Human 15-PGDH ELISA Kit

Sandwich ELISA - Human 15-PGDH ELISA Kit (AB309433)

  • 0
  • 0
Assay Kits

AB252359

Human Complement factor H ELISA Kit

Recombinant|SimpleStep

ELISA - Human Complement factor H ELISA Kit (AB252359)

  • 0
  • 0
Assay Kits

AB239420

Mouse Cathepsin D ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Mouse Cathepsin D ELISA Kit (AB239420)

  • 0
  • 0
Assay Kits

AB124539

Human ATP Synthase ELISA Kit (Complex V) Profiling ELISA Kit

Sandwich ELISA - Human ATP Synthase ELISA Kit (Complex V) Profiling ELISA Kit (AB124539)

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "sELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column

제품 세부 정보

Human Cathepsin X ELISA Kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Cathepsin X in serum, plasma and cell culture supernatants. This assay employs an antibody specific for human Cathepsin X coated on a 96-well plate.
style
left-column

Recovery

[ { "sample": "Serum", "range": "74 - 133 %", "average": "= 95.9" }, { "sample": "Plasma", "range": "80 - 135 %", "average": "= 121.1" }, { "sample": "Cell culture media", "range": "105 - 140 %", "average": "= 120.2" } ]
style
left-column

제품 구성

{ "values": { "1x96Tests": { "sellingSize": "1 x 96 Tests", "publicAssetCode":"ab314828-1x96Tests", "assetComponentDetails": [ { "size":"1 x 12 mL", "name":"TMB One-Step Substrate Reagent", "number":"AB314828-CMP07", "productcode":"" }, { "size":"1 x 25 mL", "name":"20X Wash Buffer", "number":"AB314828-CMP04", "productcode":"" }, { "size":"1 x 200 µL", "name":"100X HRP-Streptavidin", "number":"AB314828-CMP03", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Biotinylated Human Cathepsin X Detection Antibody", "number":"AB314828-CMP09", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Human Cathepsin X Antibody-coated ELISA Plate", "number":"AB314828-CMP08", "productcode":"" }, { "size":"1 x 8 mL", "name":"Stop Solution; 0.2M Sulfuric Acid", "number":"AB314828-CMP06", "productcode":"" }, { "size":"1 x 15 mL", "name":"5X Assay Diluent (Item E2)", "number":"AB314828-CMP05", "productcode":"" }, { "size":"2 x 1 Vial", "name":"Lyophilized Human Cathepsin X Protein Standard", "number":"AB314828-CMP10", "productcode":"" } ] } } }
style
left-column

특성 및 보관 정보

배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
-20°C
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Cathepsin Z also known as cathepsin X or CTSZ is a lysosomal cysteine protease with a molecular weight of approximately 34 kDa. It is expressed mainly in immune cells such as macrophages and dendritic cells but also found in other tissues including liver kidney and spleen. This protease performs proteolytic functions which involve cleaving peptide bonds in proteins contributing to protein catabolism in cells. The widespread expression of Cathepsin Z suggests its involvement in various physiological processes.
Biological function summary

Cathepsin Z participates in immune response regulation and cellular adhesion processes. It belongs to the papain-like cysteine protease family. Notably it associates with integrins to influence cell-extracellular matrix interactions affecting cell migration and adhesion. By modulating these processes Cathepsin Z impacts immune surveillance and tissue remodeling demonstrating its multifaceted role in maintaining cellular homeostasis.

Pathways

Cathepsin Z engages significantly in apoptotic and antigen-presenting pathways. In apoptosis it influences cell death by degrading specific substrates involved in cell survival. It also assists in the processing of antigens within dendritic cells facilitating effective antigen presentation to T cells. Related proteins such as Cathepsin S and Cathepsin L which also partake in lysosomal pathways further illustrate the shared functionality and redundancy within this protease family enabling a robust regulatory network.

Cathepsin Z has implications in cancer progression and neurodegenerative diseases. It is often overexpressed in cancerous tissues where it aids tumor cell invasion and metastasis through degradation of extracellular components. Additionally alterations in Cathepsin Z activity are linked to Alzheimer's disease where it may affect the processing of amyloid precursor proteins similar to its interaction with other proteins like Cathepsin B. These connections highlight the potential for Cathepsin Z as a target for therapeutic intervention in various pathological conditions.
style
left-column

제품 프로토콜

style
left-column

타겟 정보

Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (PubMed : 10504234). Capable of producing kinin potentiating peptides (By similarity).
See full target information Cathepsin Z
style
left-column
style
left-column
websiteProtocolBooklet
en
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com