AB324257
Human INHBE ELISA Kit (Inhibin beta E) (ab324257) is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of INHbE in human serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
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- sELISA
Supplier Data
Sandwich ELISA - Human INHBE ELISA Kit (Inhibin beta E) (AB324257)
In order to make the calculation easier, we plot the O.D. value of the standard (X-axis) against the log of concentration of the standard (Y-axis), although concentration is the independent variable and O.D. value is the dependent variable. The O.D. values of the standard curve may vary according to the conditions of assay performance (e.g. operator, pipetting technique, washing technique or temperature effects). Typical standard curve below is provided for reference only.
보완 제품
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "cELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
제품 세부 정보
Human INHBE ELISA Kit (Inhibin beta E) (ab324257) is a competitive inhibition enzyme immunoassay technique for the in vitro quantitative measurement of INHbE in human serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Precision
[ { "reproducibilityType": "Intra", "sample": "Sample", "replicates": 3, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 10" }, { "reproducibilityType": "Inter", "sample": "Sample", "replicates": 8, "mean": null, "standardDeviation": null, "coefficientOfVariability": "< 12" } ]
Recovery
[ { "sample": "Serum", "range": "86 - 105 %", "average": "= 97" }, { "sample": "EDTA Plasma", "range": "90 - 101 %", "average": "= 94" }, { "sample": "Heparin Plasma", "range": "82 - 93 %", "average": "= 86" } ]
제품 구성
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특성 및 보관 정보
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
-20°C
적절한 장기 보관 조건
-20°C
보관 정보
Please refer to protocols
타겟 정보
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.. Activin E is a homodimer of INHBE secreted by the liver that plays a crucial role in regulating metabolic homeostasis particularly in lipid metabolism and energy homeostasis. Plays a central role in the regulation of adipose tissue lipolysis by preventing the influx of fatty acids from adipose tissue into the liver. Mechanistically, signals via ACVR1C to activate SMAD2/3 signaling, suppressing PPARG target genes in adipose tissue, thereby reducing liver lipid content and improving glycemic control (PubMed : 38533769). Induces beige adipocyte formation and thermogenesis in response to cold exposure (By similarity).
대체 명칭 보기
Inhibin beta E chain, Activin beta-E chain, INHBE
Product promise
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