Human Retinol binding protein 4 ELISA Kit (RBP4)
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(6 제품이 사용된 논문 )
Human Retinol binding protein 4 ELISA Kit (RBP4) is a Sandwich ELISA for the measurement of Human Retinol binding protein 4 (RBP4) in Human in Biofluids, Cell/Tissue Extracts samples.
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PRO2222, RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP
- sELISA
Supplier Data
Sandwich ELISA - Human Retinol binding protein 4 ELISA Kit (RBP4) (AB108897)
Representative Standard Curve Using ab108897.
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제품 세부 정보
Abcam's Retinol binding protein 4 (RBP4) Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative measurement of Retinol binding protein 4 concentrations in plasma, serum, saliva, urine, milk, cerebrospinal fluid, cell lysates and tissue samlpes.
A Retinol binding protein 4 specific antibody has been precoated onto 96-well plates and blocked. Standards or test samples are added to the wells and subsequently a Retinol binding protein 4specific biotinylated detection antibody is added and then followed by washing with wash buffer. Streptavidin-Peroxidase Conjugate is added and unbound conjugates are washed away with wash buffer. TMB is then used to visualize Streptavidin-Peroxidase enzymatic reaction. TMB is catalyzed by Streptavidin-Peroxidase to produce a blue color product that changes into yellow after adding acidic stop solution. The density of yellow coloration is directly proportional to the amount of Retinol binding protein 4 captured in plate.
Get higher sensitivity in only 90 minutes with Human Retinol Binding Protein 4 ELISA Kit (ab196264) from our SimpleStep ELISA® range.
The entire kit may be stored at -20°C for long term storage before reconstitution - Avoid repeated freeze-thaw cycles.
Precision
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This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
RBP4 plays a role as a transporter of vitamin A from the liver to tissues where it is needed. It forms complexes with transthyretin in the blood which prevents kidney filtration and subsequent loss of retinol. This function ensures the proper delivery and availability of retinol essential for vision cellular differentiation and immune system function. The stability of the retinol-RBP4 complex is important to maintaining sufficient vitamin A levels in the body.
Pathways
RBP4 is significant in the vitamin A metabolism pathway and affects the retinoid signaling pathways. These pathways are critical for processes such as vision and skin health. RBP4 interacts with proteins like lecithin retinol acyltransferase (LRAT) in these pathways which are responsible for esterifying retinol into retinyl esters a storage form of vitamin A. These interactions ensure the efficient transport and storage of vitamin A and that it is accessible when needed by different tissues.
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제품이 사용된 논문 (6)
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Pakistan journal of medical sciences 36:1495-1499 PubMed33235563
2020
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Scientific reports 10:594 PubMed31953481
2020
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Sport sciences for health 15:551-558 PubMed31885723
2019
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Data in brief 8:536-44 PubMed27508213
2016
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Scientific reports 6:19667 PubMed26792617
2016
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Human molecular genetics 23:4077-85 PubMed24670599
2014
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