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AB235328

Anti-AGPAT1 antibody

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Rabbit Polyclonal AGPAT1 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human AGPAT1 aa 200 to C-terminus.

대체 명칭 보기

G15, AGPAT1, 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, 1-acylglycerol-3-phosphate O-acyltransferase 1, Lysophosphatidic acid acyltransferase alpha, Protein G15, 1-AGP acyltransferase 1, 1-AGPAT 1, LPAAT-alpha

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT1 antibody (AB235328)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT1 antibody (AB235328)

Paraffin-embedded human kidney tissue stained for AGPAT1 with ab235328 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT1 antibody (AB235328)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT1 antibody (AB235328)

Paraffin-embedded human placenta tissue stained for AGPAT1 with ab235328 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human AGPAT1 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q99943

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대체품

Primary Antibodies

AB67018

Anti-AGPAT1 antibody

  • 0
  • 0

보완 제품

Primary Antibodies

AB172730

Rabbit IgG, monoclonal [EPR25A] - Isotype Control

RabMAb|Advanced Validation|Recombinant

Flow Cytometry - Rabbit IgG, monoclonal [EPR25A] - Isotype Control (AB172730)

  • 0
  • 0
Primary Antibodies

AB211435

Anti-AGPAT3 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT3 antibody (AB211435)

  • 0
  • 0
Primary Antibodies

AB18184

Anti-6X His tag® antibody [HIS.H8]

Lab Essentials

Western blot - Anti-6X His tag® antibody [HIS.H8] (AB18184)

  • 5
  • 32
Primary Antibodies

AB222512

Anti-Claudin 18.2 antibody [EPR19202]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 18.2 antibody [EPR19202] (AB222512)

  • 0
  • 2
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

AGPAT1 also known as 1-acylglycerol-3-phosphate O-acyltransferase 1 performs an important role in lipid biosynthesis. It catalyzes the conversion of lysophosphatidic acid into phosphatidic acid a precursor for glycerolipid synthesis. The molecular mass of AGPAT1 is approximately 28 kDa. AGPAT1 expresses widely in human tissues with higher levels seen in adipose tissue liver and heart.
Biological function summary

AGPAT1 impacts lipid metabolism and energy homeostasis. It participates as a single enzyme and is not typically part of larger protein complexes. By facilitating the production of phosphatidic acid it influences the balance of lipid intermediates necessary for membrane and lipoprotein synthesis. This activity affects cellular processes like membrane dynamics and signal transduction.

Pathways

AGPAT1 plays an integral role in the glycerolipid metabolism pathway. It collaborates with enzymes like lipin-1 to regulate pathways that control lipid storage and release. Its action supports the phosphatidic acid pathway which connects to various cellular signaling cascades. AGPAT1 cooperates with other proteins that modulate lipid signals bringing about effects on cell proliferation and survival.

AGPAT1 associates notably with metabolic disorders and cardiovascular diseases. Dysregulation of AGPAT1 has implications for conditions like obesity and atherosclerosis as improper lipid metabolism can lead to excess lipid accumulation or energy imbalance. AGPAT1's interaction with proteins such as lipin-1 influences these disorders where lipid imbalance and chronic inflammation become important factors.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
See full target information AGPAT1
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell death & disease 10:644 PubMed31501420

2019

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ya Liu,Xiao Zhang,Jiafei Lin,Yuxin Chen,Yongxia Qiao,Susu Guo,Yueyue Yang,Guoqing Zhu,Qiuhui Pan,Jiayi Wang,Fenyong Sun
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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