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AB236541

Anti-AGPAT5 antibody

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Rabbit Polyclonal AGPAT5 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human AGPAT5 aa 150-350.

대체 명칭 보기

1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5, Lysophosphatidic acid acyltransferase epsilon, 1-AGP acyltransferase 5, 1-AGPAT 5, LPAAT-epsilon, AGPAT5

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT5 antibody (AB236541)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT5 antibody (AB236541)

Paraffin-embedded human pancreas tissue stained for AGPAT5 using ab236541 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT5 antibody (AB236541)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGPAT5 antibody (AB236541)

Paraffin-embedded human endometrial cancer tissue stained for AGPAT5 using ab236541 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human AGPAT5 aa 150-350. The exact immunogen used to generate this antibody is proprietary information.

Q9NUQ2

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대체품

Primary Antibodies

AB127749

Anti-AGPAT5 antibody

Western blot - Anti-AGPAT5 antibody (AB127749)

  • 0
  • 0

보완 제품

Proteins & Peptides

AB163064

Recombinant Human AGPAT5 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human AGPAT5 protein (GST tag N-Terminus) (AB163064)

  • 0
  • 0
Primary Antibodies

AB134130

Anti-CLSTN1 antibody [EPR2963]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-CLSTN1 antibody [EPR2963] (AB134130)

  • 5
  • 2
Primary Antibodies

AB230499

Anti-MAF1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAF1 antibody (AB230499)

  • 0
  • 0
Primary Antibodies

AB134154

Anti-TACC3 antibody [EPR7756]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-TACC3 antibody [EPR7756] (AB134154)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

AGPAT5 also known as 1-acylglycerol-3-phosphate O-acyltransferase 5 is an enzyme involved in lipid metabolism. It has a mass of approximately 47 kDa. AGPAT5 catalyzes the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA) by adding an acyl group. This enzyme is expressed in various tissues with higher levels in adipose tissue and liver. Despite its wide expression its specific regulation mechanisms remain under investigation.
Biological function summary

AGPAT5 plays a role in the biosynthesis of phospholipids and triglycerides. It is not commonly part of a large protein complex but it contributes significantly to the synthesis of important lipid molecules. These molecules are important for cell membrane formation and energy storage. AGPAT5 activity influences cellular lipid composition impacting membrane fluidity and cell signaling.

Pathways

The enzyme AGPAT5 functions within the glycerolipid metabolism pathway. It interacts directly with intermediates like lysophosphatidic acid and phosphatidic acid which are key molecules in this pathway. The enzyme also links to the phosphatidic acid biosynthesis pathway sharing functional similarities with other AGPAT family members such as AGPAT1. These interactions highlight its role in maintaining cellular lipid balance.

AGPAT5 has associations with metabolic conditions like obesity and type 2 diabetes. Changes in lipid metabolism mediated by AGPAT5 can lead to altered adipose tissue function. Through its effects on lipid pathways AGPAT5 has indirect connections with other metabolic dysregulation proteins such as hormone-sensitive lipase (HSL). Further research into AGPAT5 could provide insights into therapeutic targets for these metabolic disorders.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed : 21173190). Acts on LPA containing saturated or unsaturated fatty acids C15 : 0-C20 : 4 at the sn-1 position using C18 : 1-CoA as the acyl donor (PubMed : 21173190). Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA (PubMed : 21173190). Activity toward lysophosphatidylglycerol not detectable (PubMed : 21173190).
See full target information AGPAT5
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Pediatric research 97:1209-1219 PubMed39103629

2024

Slow rewarming after hypothermia does not ameliorate white matter injury after hypoxia-ischemia in near-term fetal sheep.

Applications

Unspecified application

Species

Unspecified reactive species

Alice McDouall,Kelly Q Zhou,Anthony Davies,Guido Wassink,Timothy L M Jones,Laura Bennet,Alistair J Gunn,Joanne O Davidson
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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