Anti-alpha 1 Fetoprotein antibody [1G7]
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(4 제품이 사용된 논문 )
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-alpha 1 Fetoprotein antibody [1G7] (AB54745)
alpha 1 Fetoprotein antibody (ab54745) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.
This image was generated using the ascites version of the product.
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-alpha 1 Fetoprotein antibody [1G7] (AB54745)
ab54745 at 10 ug/ml staining alpha Fetoprotein in human HeLa cells by Immunocytochemistry / Immunofluorescence.
This image was generated using the ascites version of the product.
- WB
Unknown
Western blot - Anti-alpha 1 Fetoprotein antibody [1G7] (AB54745)
alpha 1 Fetoprotein antibody (ab54745) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
This image was generated using the ascites version of the product.
All lanes:
Western blot - Anti-alpha 1 Fetoprotein antibody [1G7] (ab54745)
Predicted band size: 68 kDa
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- sELISA
Unknown
Sandwich ELISA - Anti-alpha 1 Fetoprotein antibody [1G7] (AB54745)
Standard Curve for Alpha 1 Fetoprotein dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal to alpha 1 Fetoprotein (ab54745) at 1ug/ml and Detector Antibody Rabbit polyclonal to alpha 1 Fetoprotein (ab8201) at 0.1ug/ml
This image was generated using the ascites version of the product.
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This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Alpha-fetoprotein functions as a fetal plasma protein with roles similar to serum albumin including the binding and transport of ligands such as bilirubin and fatty acids. It does not form part of any larger protein complex but is significant in modulating fetal immune tolerance. In the fetal environment AFP helps protect cells from maternal immune attacks by binding to estrogens and other growth-modulating factors. Its function during pregnancy is critical for maintaining homeostasis and ensuring the fetus's viability.
Pathways
Alpha 1-fetoprotein plays a role in several important biological pathways related to cellular growth and immune response modulation. One such pathway involves regulation of cell proliferation and differentiation in the developing liver. AFP interacts with cellular receptors that influence these processes. Additionally it plays a part in immune pathways interacting with elements that control immune overlooking to fetal antigens hence being linked to both hepatic and immune system proteins like albumin and estrogen receptors.
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제품이 사용된 논문 (4)
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Cells 12: PubMed36766855
2023
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ACS applied materials & interfaces 13:8823-8831 PubMed33583183
2021
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Communications biology 3:636 PubMed33128033
2020
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Oncology reports 41:2595-2600 PubMed30816512
2019
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