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AB89140

Anti-ALPK1 antibody

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(1 Publication)

Mouse Polyclonal ALPK1 antibody - Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.

대체 명칭 보기

KIAA1527, LAK, ALPK1, Alpha-protein kinase 1, Chromosome 4 kinase, Lymphocyte alpha-protein kinase

1 Images
Western blot - Anti-ALPK1 antibody (AB89140)
  • WB

Unknown

Western blot - Anti-ALPK1 antibody (AB89140)

All lanes:

Western blot - Anti-ALPK1 antibody (ab89140) at 1 µg/mL

All lanes:

HepG2 cell lysate at 50 µg

Predicted band size: 139 kDa

Observed band size: 119 kDa,37 kDa

false

주요 정보

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human ALPK1.

Q96QP1

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Serine/threonine-protein kinase that detects bacterial pathogen-associated molecular pattern metabolites (PAMPs) and initiates an innate immune response, a critical step for pathogen elimination and engagement of adaptive immunity (PubMed : 28222186, PubMed : 28877472, PubMed : 30111836). Specifically recognizes and binds ADP-D-glycero-beta-D-manno-heptose (ADP-Heptose), a potent PAMP present in all Gram-negative and some Gram-positive bacteria (PubMed : 30111836). ADP-Heptose-binding stimulates its kinase activity to phosphorylate and activate TIFA, triggering pro-inflammatory NF-kappa-B signaling (PubMed : 30111836, PubMed : 35868845, PubMed : 38060563). May be involved in monosodium urate monohydrate (MSU)-induced inflammation by mediating phosphorylation of unconventional myosin MYO9A (PubMed : 27169898). May also play a role in apical protein transport by mediating phosphorylation of unconventional myosin MYO1A (PubMed : 15883161). May play a role in ciliogenesis (PubMed : 30967659).
See full target information ALPK1

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of medical genetics 50:410-8 PubMed23539754

2013

Identification of chromosome 3q28 and ALPK1 as susceptibility loci for chronic kidney disease in Japanese individuals by a genome-wide association study.

Applications

Unspecified application

Species

Unspecified reactive species

Yoshiji Yamada,Tamotsu Nishida,Sahoko Ichihara,Kimihiko Kato,Tetsuo Fujimaki,Mitsutoshi Oguri,Hideki Horibe,Tetsuro Yoshida,Sachiro Watanabe,Kei Satoh,Yukitoshi Aoyagi,Michio Fukuda,Motoji Sawabe
제품이 사용된 논문 모두 보기

Product promise

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