AB166621

Anti-Annexin-9/ANXA9 antibody [EPR11220]

RabMAb
Recombinant
각 태그의 뜻

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(5 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal Annexin-9/ANXA9 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 5 publications.

대체 명칭 보기

ANX31, ANXA9, Annexin A9, Annexin XXXI, Annexin-31, Annexin-9, Pemphaxin

2 이미지

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Immunoprecipitation - Anti-Annexin-9/ANXA9 antibody [EPR11220] (AB166621)

Immunoprecipitation of Annexin-9/ANXA9 from pellet from Human fetal kidney lysate using ab166621 at 1/10 dilution, followed by WB detection of Annexin-9/ANXA9.

All lanes:

Immunoprecipitation - Anti-Annexin-9/ANXA9 antibody [EPR11220] (ab166621) at 1/1000 dilution

All lanes:

Immunoprecipitation pellet from fetal kidney tissue lysate at 10 µg

Predicted band size: 38 kDa

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Western blot - Anti-Annexin-9/ANXA9 antibody [EPR11220] (AB166621)

All lanes:

Western blot - Anti-Annexin-9/ANXA9 antibody [EPR11220] (ab166621) at 1/1000 dilution

Lane 1:

Human fetal kidney lysates at 10 µg

Lane 2:

Human tonsil lysates at 10 µg

Lane 3:

A431 lysates at 10 µg

Predicted band size: 38 kDa

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주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR11220

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IP

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/10 - 1/100", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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제품 세부 정보

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Annexin-9 (ANXA9) acts as a calcium/phospholipid-binding protein and belongs to the annexin family characterized by their dependency on calcium for membrane binding. ANXA9 has a molecular mass of about 36 kDa. It expresses in epithelial tissues particularly within the skin esophagus and the major airways suggesting its role in cellular homeostasis and communication in these areas. ANXA9's structure includes typical annexin repeats responsible for its binding properties and it shares similarities with other annexins.

Biological function summary

ANXA9 participates in membrane-related processes such as vesicle trafficking and membrane organization. It engages in forming stable complexes with other annexin proteins enhancing their collective functions involved in cell signaling or membrane dynamics. The protein localizes near cell membranes and aids in mediating cell-cell interactions signifying its involvement in maintaining cellular environments.

Pathways

ANXA9 connects with signaling pathways that are important for phospholipid metabolism and membrane trafficking. It interacts with proteins like ANXA1 and ANXA2 which also belong to the annexin family and perform overlapping functions in modulating cellular responses to extracellular signals. Understanding its precise role in these pathways can provide insights into its influence on cell surface receptor-mediated signaling and lipid-related metabolic processes.

Studies link ANXA9 with certain epithelial cancers given its pattern of expression in epithelial tissues. Its abnormal regulation may associate with tumor growth or progression due to its role in cell membrane stability and signal transduction. Additionally ANXA9 is associated with skin disorders where it might interact with proteins such as filaggrin contributing to barrier dysfunctions or inflammatory responses. These connections highlight the need for further research to elucidate ANXA9’s exact functions and its potential as a therapeutic target in these conditions.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Plays a role in epidermal differentiation (PubMed : 10899159). Can bind acetylcholine (PubMed : 10899159).

See full target information ANXA9

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제품이 사용된 논문 (5)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nucleic acids research 53: PubMed40586312

2025

ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA.

Applications

Unspecified application

Species

Unspecified reactive species

Adrian Soderholm,Milica Vunjak,Melanie de Almeida,Niko Popitsch,Nadezda Podvalnaya,Pablo Araguas-Rodriguez,Sara Scinicariello,Emily Nischwitz,Falk Butter,René F Ketting,Stefan L Ameres,Michaela Müller-McNicoll,Johannes Zuber,Gijs A Versteeg

Cell death & disease 15:260 PubMed38609357

2024

ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Xiqian Zhou,Junyong Zhao,Tao Yan,Danrong Ye,Yuying Wang,Bai'an Zhou,Diya Liu,Xuehui Wang,Wenfang Zheng,Bowen Zheng,Fengyuan Qian,Yating Li,Dengfeng Li,Lin Fang

Frontiers in oncology 13:1166666 PubMed37841425

2023

miR-186-ANXA9 signaling inhibits tumorigenesis in breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Zhongrui Wang,Xiqian Zhou,Xiaochong Deng,Danrong Ye,Diya Liu,Baian Zhou,Wenfang Zheng,Xuehui Wang,Yuying Wang,Oyungerel Borkhuu,Lin Fang

The journal of pathology. Clinical research 9:378-390 PubMed37294149

2023

Exosome-derived ANXA9 functions as an oncogene in breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Cuiping Lu,Ying Zhan,Yunshan Jiang,Jianrong Liao,Zidan Qiu

Translational lung cancer research 12:1062-1077 PubMed37323183

2023

Harmine loaded Au@MSNs@PEG@Asp6 nano-composites for treatment of spinal metastasis from lung adenocarcinoma by targeting ANXA9 experiment.

Applications

Unspecified application

Species

Unspecified reactive species

Houlei Wang,Fancheng Chen,Annan Hu,Haifeng Liang,Yun Liang,Nagashree Seetharamu,Huiren Wang,Jian Dong

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Annexin-9/ANXA9 antibody [EPR11220]

Immunoprecipitation - Anti-Annexin-9/ANXA9 antibody [EPR11220] (AB166621)

Western blot - Anti-Annexin-9/ANXA9 antibody [EPR11220] (AB166621)

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (5)

Product promise