AB72040

Anti-APC antibody

5

(2 리뷰들)

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(4 제품이 사용된 논문 )

Rabbit Polyclonal APC antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human APC.

1 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC antibody (AB72040)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC antibody (AB72040)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling APC with ab72040 at 1/1000 (1µg/ml). Detection : DAB.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

Immunogen

Synthetic Peptide within Human APC. The exact immunogen used to generate this antibody is proprietary information.

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대체품

Primary Antibodies

AB40778

Anti-APC antibody [EP701Y]

BOND RX™ Validated|RabMAb|Recombinant|20ul selling size

Flow Cytometry (Intracellular) - Anti-APC antibody [EP701Y] (AB40778)

3
2

Primary Antibodies

AB58

Anti-APC antibody [ALi 12-28]

Flow Cytometry - Anti-APC antibody [ALi 12-28] (AB58)

2
2

Primary Antibodies

AB16794

Anti-APC antibody [CC-1]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC antibody [CC-1] (AB16794)

4
5

Primary Antibodies

AB245442

Anti-APC antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC antibody (AB245442)

0
0

Primary Antibodies

AB239828

Anti-APC antibody [EP701Y] - BSA and Azide free

BOND RX™ Validated|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-APC antibody [EP701Y] - BSA and Azide free (AB239828)

0
0

Primary Antibodies

AB265597

Anti-APC antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APC antibody (AB265597)

0
0

보완 제품

Primary Antibodies

AB109186

Anti-Olig2 antibody [EPR2673] - Oligodendrocyte Marker

BOND RX™ Validated|20ul selling size|Recombinant|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Olig2 antibody [EPR2673] - Oligodendrocyte Marker (AB109186)

5
22

Primary Antibodies

AB7349

Anti-Myelin Basic Protein antibody [12] - Oligodendrocyte Marker

BOND RX™ Validated|Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin Basic Protein antibody [12] - Oligodendrocyte Marker (AB7349)

4
23

Primary Antibodies

AB278054

Anti-GFAP antibody [RM1003] - Astrocyte Marker

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFAP antibody [RM1003] - Astrocyte Marker (AB278054)

0
0

Primary Antibodies

AB16667

Anti-Ki67 antibody [SP6]

BOND RX™ Validated|KO Validated|RabMAb|Advanced Validation|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ki67 antibody [SP6] (AB16667)

5
133

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/2000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Chicken": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Chimpanzee": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Dog": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Guinea pig": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Horse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Pig": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Platypus": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rabbit": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rhesus monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Xenopus tropicalis": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

Purification 관련 사항

ab72040 was affinity purified using an epitope specific to APC immobilized on solid support.

보관 버퍼

pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: PBS, 1.815% Tris, 1.764% Sodium citrate

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

+4°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Associates with both microtubules and actin filaments, components of the cytoskeleton (PubMed : 17293347). Plays a role in mediating the organization of F-actin into ordered bundles (PubMed : 17293347). Functions downstream of Rho GTPases and DIAPH1 to selectively stabilize microtubules (By similarity). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

See full target information APC

대체 명칭 보기

DP2.5, APC, Adenomatous polyposis coli protein, Protein APC, Deleted in polyposis 2.5

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제품이 사용된 논문 (4)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature communications 12:2678 PubMed33976153

2021

Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.

Applications

Unspecified application

Species

Unspecified reactive species

Marija Kojic,Tomasz Gawda,Monika Gaik,Alexander Begg,Anna Salerno-Kochan,Nyoman D Kurniawan,Alun Jones,Katarzyna Drożdżyk,Anna Kościelniak,Andrzej Chramiec-Głąbik,Soroor Hediyeh-Zadeh,Maria Kasherman,Woo Jun Shim,Enakshi Sinniah,Laura A Genovesi,Rannvá K Abrahamsen,Christina D Fenger,Camilla G Madsen,Julie S Cohen,Ali Fatemi,Zornitza Stark,Sebastian Lunke,Joy Lee,Jonas K Hansen,Martin F Boxill,Boris Keren,Isabelle Marey,Margarita S Saenz,Kathleen Brown,Suzanne A Alexander,Sergey Mureev,Alina Batzilla,Melissa J Davis,Michael Piper,Mikael Bodén,Thomas H J Burne,Nathan J Palpant,Rikke S Møller,Sebastian Glatt,Brandon J Wainwright

Aging 12:23808-23821 PubMed33176278

2020

Effect of Klotho protein during porcine oocyte maturation via Wnt signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Eui Hyun Kim,Anukul Taweechaipaisankul,Muhammad Rosyid Ridlo,Geon A Kim,Byeong Chun Lee

Theranostics 10:74-90 PubMed31903107

2020

Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion.

Applications

Unspecified application

Species

Unspecified reactive species

Lin-Yuan Zhang,Jiaji Pan,Muyassar Mamtilahun,Yuan Zhu,Liping Wang,Ashwin Venkatesh,Rubing Shi,Xuanqiang Tu,Kunlin Jin,Yongting Wang,Zhijun Zhang,Guo-Yuan Yang

Scientific reports 9:10783 PubMed31346222

2019

GRP78 translocation to the cell surface and O-GlcNAcylation of VE-Cadherin contribute to ER stress-mediated endothelial permeability.

Applications

Unspecified application

Species

Unspecified reactive species

Raji Lenin,Peter G Nagy,Kumar Abhiram Jha,Rajashekhar Gangaraju

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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